Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: do adipocytes consume sufficient amounts of oxygen to oxidise fatty acids?

被引:10
|
作者
Maassen, J. A. [1 ,2 ]
Romijn, J. A. [3 ]
Heine, R. J. [2 ,4 ]
机构
[1] Leiden Univ, Med Ctr, Dept Mol Cell Biol, NL-2300 RC Leiden, Netherlands
[2] Vrije Univ Amsterdam, Dept Endocrinol, Ctr Diabet, Med Ctr, Amsterdam, Netherlands
[3] Leiden Univ, Med Ctr, Dept Endocrinol & Metab Dis, Leiden, Netherlands
[4] Eli Lilly & Co, Lilly Corp Ctr, Indianapolis, IN 46285 USA
关键词
adipocytes; fatty acids; HAART; mitochondria; type 2 diabetes mellitus;
D O I
10.1007/s00125-008-0963-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:907 / 908
页数:2
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