The domestic dog: man's best friend in the genomic era

被引:82
|
作者
Boyko, Adam R. [1 ]
机构
[1] Stanford Univ, Dept Genet, Stanford, CA 94305 USA
来源
GENOME BIOLOGY | 2011年 / 12卷 / 02期
关键词
LINKAGE DISEQUILIBRIUM; MUTATION; SELECTION; WOLVES; LOCI; MULTIPLE; VARIANTS; REVEALS; BIOLOGY; HISTORY;
D O I
10.1186/gb-2011-12-2-216
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The domestic dog genome - shaped by domestication, adaptation to human-dominated environments and artificial selection - encodes tremendous phenotypic diversity. Recent developments have improved our understanding of the genetics underlying this diversity, unleashing the dog as an important model organism for complex-trait analysis.
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页数:10
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