Laparoscopic Hyperthermic Intraperitoneal Peroperative Chemotherapy (HIPEC) in the Management of Refractory Malignant Ascites: A Multi-Institutional Retrospective Analysis in 52 Patients

被引:69
作者
Valle, M. [2 ]
Van der Speeten, K. [1 ]
Garofalo, A. [2 ]
机构
[1] Ziekenhuis Oost Limburg, Dept Surg Oncol, B-3600 Genk, Belgium
[2] Regina Elena Inst Canc Res, Digest Branch, Dept Surg Oncol, Rome, Italy
关键词
malignant ascites; laparoscopy; chemotherapy; intraperitoneal; PERITONEAL CARCINOMATOSIS; CYTOREDUCTIVE SURGERY; INTRAABDOMINAL PRESSURE; EFFICACY; GROWTH; CANCER; PHARMACOKINETICS; PALLIATION;
D O I
10.1002/jso.21321
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Malignant ascites is a debilitating condition affecting cancer patients in their terminal stage of disease. Recently, laparoscopic hyperthermic intraperitoneal peroperative chemotherapy (HIPEC) was introduced as a new approach. From September 2001 to August 2008, 52 patients were treated with this new modality. No treatment-related mortality was observed. Median survival was 98 days. One patient developed a clinical recurrence. Laparoscopic HIPEC is a safe and effective method for palliating malignant ascites J. Surg. Oncol. 2009;100:331-334. (C) 2009 Wiley-Liss, Inc.
引用
收藏
页码:331 / 334
页数:4
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