A standard calculation methodology for human doubly labeled water studies

被引：86

作者：

Speakman, John R. ^{[1
,2
,3
,4
]}

Yamada, Yosuke ^{[5
,6
]}

Sagayama, Hiroyuki ^{[7
]}

Berman, Elena S. F. ^{[8
]}

Ainslie, Philip N. ^{[9
]}

Andersen, Lene F. ^{[10
]}

Anderson, Liam J. ^{[9
,11
]}

Arab, Lenore ^{[12
]}

Baddou, Issaad ^{[13
]}

Bedu-Addo, Kweku ^{[14
]}

Blaak, Ellen E. ^{[15
]}

Blanc, Stephane ^{[16
,17
]}

Bonomi, Alberto G. ^{[18
]}

Bouten, Carlijn V. C. ^{[19
,20
]}

Bovet, Pascal ^{[21
]}

Buchowski, Maciej S. ^{[22
]}

Butte, Nancy F. ^{[23
]}

Camps, Stefan G. J. A. ^{[15
]}

Close, Graeme L. ^{[9
]}

Cooper, Jamie A. ^{[16
]}

Creasy, Seth A. ^{[24
]}

Das, Sai Krupa ^{[25
]}

Cooper, Richard ^{[26
]}

Dugas, Lara R. ^{[26
]}

Ebbeling, Cara B. ^{[27
]}

Ekelund, Ulf ^{[28
]}

Entringer, Sonja ^{[29
,30
,31
,32
,33
]}

Forrester, Terrence ^{[34
]}

Fudge, Barry W. ^{[35
]}

Goris, Annelies H. ^{[15
]}

Gurven, Michael ^{[36
]}

Hambly, Catherine ^{[2
]}

El Hamdouchi, Asmaa ^{[13
]}

Hoos, Marije B. ^{[15
]}

Hu, Sumei ^{[3
]}

Joonas, Noorjehan ^{[37
]}

Joosen, Annemiek M. ^{[15
]}

Katzmarzyk, Peter ^{[38
]}

Kempen, Kitty P. ^{[15
]}

Kimura, Misaka ^{[6
]}

Kraus, William E. ^{[39
]}

Kushner, Robert F. ^{[40
]}

Lambert, Estelle, V ^{[41
]}

Leonard, William R. ^{[42
]}

Lessan, Nader ^{[43
]}

Ludwig, David S. ^{[27
]}

Martin, Corby K. ^{[38
]}

Medin, Anine C. ^{[10
,44
]}

Meijer, Erwin P. ^{[15
]}

Morehen, James C. ^{[9
,45
]}

机构：

[1] Chinese Acad Sci, Ctr Energy Metab & Reprod, Shenzhen Inst Adv Technol, Shenzhen, Peoples R China

[2] Univ Aberdeen, Inst Biol & Environm Sci, Aberdeen, Scotland

[3] Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Mol Dev Biol, Beijing, Peoples R China

[4] CAS Ctr Excellence Anim Evolut & Genet, Kunming, Yunnan, Peoples R China

[5] Natl Inst Hlth & Nutr, Natl Inst Biomed Innovat, Hlth & Nutr, Tokyo, Japan

[6] Kyoto Univ Adv Sci, Inst Act Hlth, Kyoto, Japan

[7] Univ Tsukuba, Fac Hlth & Sport Sci, Ibaraki, Japan

[8] Berman Sci Consulting, Mountain View, CA USA

[9] Liverpool John Moores Univ, Res Inst Sport & Exercise Sci, Liverpool, Merseyside, England

[10] Univ Oslo, Inst Basic Med Sci, Dept Nutr, N-0317 Oslo, Norway

[11] Crewe Alexandra Football Club, Crewe, England

[12] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA

[13] AFRA IAEA, Reg Designated Ctr Nutr, Univ Ibn Tofail URAC39, Unite Mixte Rech Nutr & Alimentat,CNESTEN, Rabat, Morocco

[14] Kwame Nkrumah Univ Sci & Technol, Dept Physiol, Kumasi, Ghana

[15] Maastricht Univ, Maastricht, Netherlands

[16] Univ Wisconsin, Nutr Sci, Madison, WI USA

[17] Univ Strasbourg, Inst Pluridisciplinaire Hubert Curien, UMR7178, CNRS, Strasbourg, France

[18] Phillips Res, Eindhoven, Netherlands

[19] Eindhoven Univ Technol, Dept Biomed Engn, Eindhoven, Netherlands

[20] Eindhoven Univ Technol, Inst Complex Mol Syst, Eindhoven, Netherlands

[21] Lausanne Univ Hosp, Inst Social & Prevent Med, Lausanne, Switzerland

[22] Vanderbilt Univ, Dept Med, Div Gastroenterol Hepatol & Nutr, Nashville, TN USA

[23] Baylor Coll Med, USDA, ARS, Childrens Nutr Res Ctr,Dept Pediat, Houston, TX 77030 USA

[24] Univ Colorado, Div Endocrinol Metab & Diabet, Anschulz Med Campus, Aurora, CO USA

[25] Tufts Univ, Friedman Sch Nutr Sci & Policy, 150 Harrison Ave, Boston, MA 02111 USA

[26] Loyola Univ, Dept Publ Hlth Sci, Parkinson Sch Hlth Sci & Publ Hlth, Maywood, IL 60153 USA

[27] Boston Childrens Hosp, Boston, MA USA

[28] Norwegian Sch Sport Sci, Dept Sport Med, Oslo, Norway

[29] Charite Univ Med Berlin, Berlin, Germany

[30] Free Univ Berlin, Berlin, Germany

[31] Humboldt Univ, Berlin, Germany

[32] Berlin Inst Hlth BIH, Inst Med Psychol, Berlin, Germany

[33] Univ Calif Irvine, Irvine, CA USA

[34] Univ West Indies, Solut Developing Countries, Kingston, Jamaica

[35] Univ Glasgow, Glasgow, Lanark, Scotland

[36] Univ Calif Santa Barbara, Dept Anthropol, Santa Barbara, CA 93106 USA

[37] Minist Hlth & Wellness, Cent Hlth Lab, Port Louis, Mauritius

[38] Pennington Biomed Res Ctr, 6400 Perkins Rd, Baton Rouge, LA 70808 USA

[39] Duke Univ, Dept Med, Durham, NC USA

[40] Northwestern Univ, Chicago, IL 60611 USA

[41] Univ Cape Town, Res Unit Exercise Sci & Sports Med, Cape Town, South Africa

[42] Northwestern Univ, Dept Anthropol, Evanston, IL 60208 USA

[43] Imperial Coll London, Imperial Coll London Diabet Ctr, London, England

[44] Univ Agder, Fac Hlth & Sport Sci, Dept Nutr & Publ Hlth, N-4630 Kristiansand, Norway

[45] FA Grp, Burton Upon Trent, Staffs, England

[46] Univ Washington, Div Publ Hlth Sci, Fred Hutchinson Canc Res Ctr, Seattle, WA 98195 USA

[47] Univ Washington, Sch Publ Hlth, Seattle, WA 98195 USA

[48] Moi Univ, Eldoret, Kenya

[49] Univ Global Hlth Equ, Kigali, Rwanda

[50] Helsinki Univ Cent Hosp, Helsinki, Finland

来源：

CELL REPORTS MEDICINE | 2021年 / 2卷 / 02期

基金：

美国国家科学基金会;

关键词：

CARBON-DIOXIDE PRODUCTION; DILUTION SPACE RATIO; ENERGY-EXPENDITURE; CO2; PRODUCTION; BODY-WATER; VALIDATION; O-18; H-2; INFANTS;

D O I：

10.1016/j.xcrm.2021.100203

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The doubly labeled water (DLW) method measures total energy expenditure (TEE) in free-living subjects. Several equations are used to convert isotopic data into TEE. Using the International Atomic Energy Agency (IAEA) DLW database (5,756 measurements of adults and children), we show considerable variability is introduced by different equations. The estimated rCO(2) is sensitive to the dilution space ratio (DSR) of the two isotopes. Based on performance in validation studies, we propose a new equation based on a new estimate of the mean DSR. The DSR is lower at low body masses (<10 kg). Using data for 1,021 babies and infants, we show that the DSR varies non-linearly with body mass between 0 and 10 kg. Using this relationship to predict DSR from weight provides an equation for rCO(2) over this size range that agrees well with indirect calorimetry (average difference 0.64%; SD = 12.2%). We propose adoption of these equations in future studies.

引用

页数：13

共 32 条

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