Clostridium Difficile and Inflammatory Bowel Disease

被引:49
作者
Ananthakrishnan, Ashwin N. [2 ]
Issa, Mazen [2 ]
Binion, David G. [1 ]
机构
[1] Univ Pittsburgh, Sch Med, UPMC IBD Ctr, Div Gastroenterol Hepatol & Nutr, Pittsburgh, PA 15213 USA
[2] Med Coll Wisconsin, Div Gastroenterol & Hepatol, Milwaukee, WI 53226 USA
关键词
Clostridium difficile; Inflammatory bowel disease; Crohn disease; Ulcerative colitis; Colectomy; TOXIN-A; PSEUDOMEMBRANOUS COLITIS; RISK-FACTORS; DIARRHEA; INFECTION; VANCOMYCIN; METRONIDAZOLE; DIAGNOSIS; ENTERITIS; OUTBREAK;
D O I
10.1016/j.gtc.2009.07.003
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The past decade has seen an alarming increase in the burden of disease associated with Clostridium difficile. Several studies have now demonstrated an increasing incidence of C difficile infection in patients with inflammatory bowel disease (IBD) with a more severe course of disease compared with the non-IBD population. This article summarizes the available literature on the impact of C difficile infection on IBD and discusses the various diagnostic testing and treatment options available. Also reviewed are clinical situations specific to patients with IBD that are important for the treating physician to recognize.
引用
收藏
页码:711 / +
页数:19
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