Molecular and genetic approaches to studying exercise performance and adaptation

被引:5
作者
Allen, DL
Harrison, BC
Leinwand, LA
机构
[1] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA
[2] Univ Colorado, Dept Kinesiol & Appl Physiol, Boulder, CO 80309 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2002年 / 30卷 / 03期
关键词
transgenic; skeletal muscle; cardiac muscle; hypertrophy; endurance exercise; plasticity; promoter;
D O I
10.1097/00003677-200207000-00002
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The increasing availability of molecular biological techniques has allowed exercise researchers to examine the molecular mechanisms underlying exercise performance and adaptation. We discuss three molecular approaches that can evaluate the role of individual genes in the exercise response, and could provide a foundation for more effective exercise regimens for humans.
引用
收藏
页码:99 / 105
页数:7
相关论文
共 50 条
  • [41] High-intensity leg cycling alters the molecular response to resistance exercise in the arm muscles
    Moberg, Marcus
    Apro, William
    Cervenka, Igor
    Ekblom, Bjoern
    van Hall, Gerrit
    Holmberg, Hans-Christer
    Ruas, Jorge L.
    Blomstrand, Eva
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [42] Omics and Exercise: Global Approaches for Mapping Exercise Biological Networks
    Hoffman, Nolan J.
    COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, 2017, 7 (10):
  • [43] Muscles proteome analysis; irisin administration mimics some molecular effects of exercise in quadriceps muscle
    Momenzadeh, Sedigheh
    Zamani, Saeed
    Pourteymourfard-Tabrizi, Zahra
    Barreiro, Carlos
    Jami, Mohammad-Saeid
    BIOCHIMIE, 2021, 189 : 144 - 157
  • [44] Mimicking exercise in three-dimensional bioengineered skeletal muscle to investigate cellular and molecular mechanisms of physiological adaptation
    Kasper, Andreas M.
    Turner, Daniel C.
    Martin, Neil R. W.
    Sharples, Adam P.
    JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 233 (03) : 1985 - 1998
  • [45] The Limits of Exercise Physiology: From Performance to Health
    Gabriel, Brendan M.
    Zierath, Juleen R.
    CELL METABOLISM, 2017, 25 (05) : 1000 - 1011
  • [46] Exercise-induced histone H3 trimethylation at lysine 27 facilitates the adaptation of skeletal muscle to exercise in mice
    Shimizu, Junya
    Kawano, Fuminori
    JOURNAL OF PHYSIOLOGY-LONDON, 2022, 600 (14): : 3331 - 3353
  • [47] Benefits of exercise training on cardiovascular dysfunction: molecular and integrative
    Zucker, Irving H.
    Musch, Timothy, I
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2018, 315 (04): : H1027 - H1031
  • [48] Going nuclear: Molecular adaptations to exercise mediated by myonuclei
    Koopmans, Pieter J.
    Zwetsloot, Kevin A.
    Murach, Kevin A.
    SPORTS MEDICINE AND HEALTH SCIENCE, 2023, 5 (01) : 2 - 9
  • [49] Genetic research and testing in sport and exercise science: A review of the issues
    Wackerhage, Henning
    Miah, Andy
    Harris, Roger C.
    Montgomery, Hugh E.
    Williams, Alun G.
    JOURNAL OF SPORTS SCIENCES, 2009, 27 (11) : 1109 - 1116
  • [50] Molecular Basis for the Therapeutic Effects of Exercise on Mitochondrial Defects
    Memme, Jonathan M.
    Hood, David A.
    FRONTIERS IN PHYSIOLOGY, 2021, 11