Paediatric hepatitis C virus infection and its treatment: Present, past, and future

被引：2
|
作者：
El-Shabrawi, Mortada [1 ]
Hassanin, Fetouh [2 ]
机构：
[1] Cairo Univ, Fac Med, Paediat Dept, Cairo, Egypt
[2] Misr Int Univ, Cairo, Egypt
来源：
ARAB JOURNAL OF GASTROENTEROLOGY | 2019年 / 20卷 / 03期
关键词：
HCV; Children; Treatment; DAAs; DIRECT-ACTING ANTIVIRALS; TRANSFUSION-ASSOCIATED HEPATITIS; SUSTAINED VIROLOGICAL RESPONSE; TERM HISTOLOGIC IMPROVEMENT; DACLATASVIR PLUS SOFOSBUVIR; QUALITY-OF-LIFE; CHRONIC NON-A; INTERFERON-ALPHA; VIRAL-HEPATITIS; RIBAVIRIN TREATMENT;
D O I：
10.1016/j.ajg.2019.09.003
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease in the world. It is a challenging medico-social problem in the paediatric population. High HCV infection rates are reported in low and middle incomes countries. From the health economic point of view treatment of hepatitis C virus (HCV) with subsequent virus eradication is very effective as it eliminates the long-term sequelae of untreated or maltreated HCV In this review we summarize the updates and highlight the historical approach of treatment of chronic HCV infection in children in the new era of directly acting antiviral (DAA) agents. (C) 2019 Pan-Arab Association of Gastroenterology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：163 / 174
页数：12
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