Cutaneous aspergillosis in a lung transplant recipient

被引:8
|
作者
Ramos, A. [1 ,2 ]
Ussetti, P. [3 ]
Laporta, R. [3 ]
Lazaro, M. T. [3 ]
Sanchez-Romero, I. [4 ]
机构
[1] Univ Autonoma Madrid, Med Interna Serv, Hosp Univ Puerta de Hierro, Dept Internal Med, Madrid 28222, Spain
[2] Univ Autonoma Madrid, Spanish Network Res Infect Dis REIPI, Hosp Univ Puerta de Hierro, Madrid 28222, Spain
[3] Univ Autonoma Madrid, Dept Pneumol, Hosp Univ Puerta de Hierro, Madrid 28222, Spain
[4] Univ Autonoma Madrid, Dept Microbiol, Hosp Univ Puerta de Hierro, Madrid 28222, Spain
关键词
Aspergillus fumigatus; skin diseases; cutaneous infections; lung transplantation; INVASIVE ASPERGILLOSIS; AMPHOTERICIN-B; INFECTION; VORICONAZOLE; SPECTRUM; FUNGI; USTUS;
D O I
10.1111/j.1399-3062.2009.00423.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P>Organ transplant recipients are at increased risk for Aspergillus infections. Cutaneous aspergillosis (CA) occurs less frequently and is poorly characterized. The case of a lung transplant recipient with CA is presented. Six months after transplantation, 3 painful skin nodules appeared, with 1 each in the right calf, left arm, and upper back. Exudate from the leg nodule yielded Aspergillus fumigatus. Computed tomography of the chest showed bilateral hilar lymphadenopathy, but < 1 cm in size. The case could be the result of Aspergillus dissemination from a hypothetical asymptomatic pulmonary infection. The lack of lung radiological signs could be related to prophylactic treatment with inhaled liposomal amphotericin B, which could have prevented clinically evident Aspergillus lung infection. The patient was treated with voriconazole, which was maintained for 3 months. The patient recovered completely.
引用
收藏
页码:471 / 473
页数:3
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