Organ Damage and Quality of Life in Antiphospholipid Syndrome

被引：10

作者：

Alba, P. ^{[1
]}

Gomez-Puerta, J. A. ^{[2
]}

Goycochea-Robles, M. V. ^{[3
]}

Amigo, M. C. ^{[4
]}

机构：

[1] Univ Nacl Cordoba, Hosp Cordoba, Catedra Med 1, UHMI 3, Libertad 2051, RA-5000 Cordoba, Argentina

[2] Univ Antioquia, Grp Inmunol Celular & Inmunogenet GICIG, Calle 67 53-108, Medellin, Colombia

[3] Univ Nacl Autonoma Mexico, Hosp Gen Reg 1, IMSS, Unidad Invest Epidemiol Clin, Gabriel Mancera 222, Mexico City 03100, DF, Mexico

[4] Univ Nacl Autonoma Mexico, Ctr Med ABC, Sur 136 116, Mexico City 01120, DF, Mexico

来源：

CURRENT RHEUMATOLOGY REPORTS | 2016年 / 18卷 / 02期

关键词：

Systemic autoimmune diseases (SAD); Organ damage; Quality of life; Health-related quality of life (HRQoL); Antiphospholipid syndrome (APS); Damage index in APS (DIAPS); SLICC/ACR Damage Index (SDI); SYSTEMIC-LUPUS-ERYTHEMATOSUS; COLLABORATING CLINICS/AMERICAN-COLLEGE; INTERNATIONAL CONSENSUS STATEMENT; SYNDROME APS; CLASSIFICATION CRITERIA; PROGNOSTIC-FACTORS; MORTALITY; INDEX; RHEUMATOLOGY; SF-36;

D O I：

10.1007/s11926-015-0556-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antiphospholipid syndrome (APS) affects young patients in the most productive years of their life, and the consequences of organic or tissue damage involve a decrease in health-related quality of life (HRQoL). While acute disease manifestations of APS are well known, information on the long-term prognosis and damage in affected patients is still very limited. Systemic lupus erythematosus (SLE) patients would be expected to experience long-term complications and even die as a consequence of APS. Organ damage in APS has been evaluated using different methods and definitions, including the SLICC/ACR Damage Index (SDI), which tend to underestimate aPL-related damage. A new damage index in APS has been proposed (DIAPS), and it seems to be more accurate than SDI. Given the implications for morbidity and mortality, it is imperative to assess accurately aPL-related damage and HRQoL in patients with APS.

引用

页码：1 / 7

页数：7

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