Immunomodulatory properties of silver-containing nanocomposite on the basis of polyvinyltriazole

被引:19
作者
Prozorova, G. F. [1 ]
Korzhova, S. A. [1 ]
Pozdnyakov, A. S. [1 ]
Emel'yanov, A. I. [1 ]
Ermakova, T. G. [1 ]
Dubrovina, V. I. [2 ]
机构
[1] Russian Acad Sci, AE Favorsky Irkutsk Inst Chem, Siberian Branch, 1 Ul Favorskogo, Irkutsk 664033, Russia
[2] Irkutsk Antiplague Res Inst Siberia & Far East, Irkutsk 664047, Russia
基金
俄罗斯基础研究基金会;
关键词
poly-1-vinyl-1,2,4-triazole; nanocomposite; silver nanoparticles; immuno-modulatory properties; NANOPARTICLES;
D O I
10.1007/s11172-015-1028-x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The water-soluble nanocomposite with the uniform distribution of silver nanoparticles in polymer matrix was synthesized on the basis of poly-1-vinyl-1,2,4-triazole. Physicochemical and immunomodulatory properties of the nanocomposite were studied. The stimulating effect of the nanocomposite on the functional capability of phagocytes in vitro and potential of using it as a drug, which increases the natural resistance of organism against infectious agents, were established.
引用
收藏
页码:1437 / 1439
页数:3
相关论文
共 15 条
[1]  
[Anonymous], 2000, Metal Nanoparticles in Polymers
[2]  
Blagitko E. M., 2004, RF Patent, Patent No. [2233652C1, 2233652]
[3]  
Broz P, 2010, RSC NANOSCI NANOTECH, P1, DOI 10.1039/9781847559968
[4]   Structure and characteristics of film composites based on methyl cellulose, poviargol, and montmorillonite [J].
Dobrovol'skaya, I. P. ;
Yudin, V. E. ;
Drozdova, N. F. ;
Smirnova, V. E. ;
Gofman, I. V. ;
Popova, E. N. ;
Bochek, A. M. ;
Zabivalova, N. M. ;
Plugar', I. V. ;
Panarin, E. F. .
POLYMER SCIENCE SERIES A, 2011, 53 (02) :166-171
[5]  
Dubrovina V. I., 2011, OPREDELENIE FUNKTSYO
[6]  
Ermakova TG, 1997, ZH OBSHCH KHIM+, V67, P859
[7]  
Gordon A., 1976, SPUTNIK KHIMIKA
[8]  
Korbekandi H, 2012, DELIVERY OF NANOPARTICLES, P3
[9]  
Krutyakov YA, 2008, USP KHIM+, V77, P242
[10]   Metal nanoparticles in condensed media: preparation and the bulk and surface structural dynamics [J].
Olenin, A. Yu ;
Lisichkin, G. V. .
RUSSIAN CHEMICAL REVIEWS, 2011, 80 (07) :605-630