Synthesis of the C19-C34 segment of amphidinolide C

被引：34

作者：

Mohapatra, Debendra K. ^{[1
]}

Rahaman, Hasibur

Chorghade, Mukund S.

Gurjar, Mukund K.

机构：

[1] Natl Chem Lab, Div Organ Chem Technol, Pune 411008, Maharashtra, India

[2] Chorghade Enterprises, Natick, MA 01760 USA

来源：

SYNLETT | 2007年 / 04期

关键词：

amphidinolide C; cytotoxic; ring-closing metathesis; Wittig reaction; Nozaki-Hiyama-Kishi coupling;

D O I：

10.1055/s-2007-967968

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the C19-C34 segment of amphidinolide C is described. The key steps include the Mioskowski's Lewis acid catalyzed epoxide opening with the alcohol, ring-closing metathesis, Wittig reaction, and Nozaki-Hiyama-Kishi coupling reaction.

引用

页码：567 / 570

页数：4

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