Intermediate filament expression of ductal carcinoma cells in fine needle aspirates of the breast

被引：0
作者：
Heatley, M [1 ]
White, J [1 ]
Patterson, A [1 ]
Maxwell, P [1 ]
Whiteside, C [1 ]
Toner, P [1 ]
机构：
[1] ROYAL VICTORIA HOSP,DEPT PATHOL,BELFAST BT12 6BA,ANTRIM,NORTH IRELAND
来源：
ACTA CYTOLOGICA | 1997年 / 41卷 / 03期
关键词：
intermediate filament proteins; breast neoplasms; carcinoma; ductal; cytological techniques; MAMMARY EPITHELIAL-CELLS; ESTROGEN-RECEPTOR; VIMENTIN EXPRESSION; KI-67; CANCER; PROGNOSIS; FRACTION; ANTIBODY; BENIGN;
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
OBJECTIVE: To assess the frequency of occurrence of vimentin expression in fine needle aspirates of ductal carcinoma of the breast and the association of vimentin expression with established prognostic indicators. STUDY DESIGN: Cytocentrifuge preparations made from fine needle aspirates of 51 cases of ductal carcinoma were studied. RESULTS: Vimentin expression, detected in 61% of cases, was positively associated with tumor size, lymph node status, turner grade, growth fraction and negative estrogen receptor status, but only in the case of lymph node status did the association each the level of statistical significance. CONCLUSION: Vimentin expression can be detected in breast cancer using fine needle aspiration. Further study is necessary to determine whether it provides independent prognostic information.
引用
收藏
页码：717 / 720
页数：4
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