Leprosy in Children

被引：23

作者：

Barreto, Josafa Goncalves ^{[1
]}

Cipriani Frade, Marco Andrey ^{[2
]}

Bernardes Filho, Fred ^{[2
]}

da Silva, Moises Batista ^{[3
]}

Spencer, John Stewart ^{[4
]}

Salgado, Claudio Guedes ^{[3
]}

机构：

[1] Fed Univ Para, Spatial Epidemiol Lab, Campus Castanhal,Ave Univ S-N, BR-68746360 Bairro Jaderlandia Casta, Para, Brazil

[2] Univ Sao Paulo, Dept Ribeirao Preto Med Sch, Div Dermatol Internal Med, Av Bandeirantes 3900, BR-14049900 Ribeirao Preto, SP, Brazil

[3] Fed Univ Para, Dermatoimmunol Lab, Av Joao Paulo II,113 Bairro Dom Aristides, BR-67200000 Marituba, Para, Brazil

[4] Colorado State Univ, Dept Microbiol Immunol & Pathol, 1682 Campus Delivery, Ft Collins, CO 80523 USA

来源：

CURRENT INFECTIOUS DISEASE REPORTS | 2017年 / 19卷 / 06期

关键词：

Leprosy; Early diagnosis; Children; LATERAL FLOW ASSAY; CHILDHOOD LEPROSY; MYCOBACTERIUM-LEPRAE; CHEMOPROPHYLAXIS; COMBINATION; INFECTION; RATES; INDIA;

D O I：

10.1007/s11908-017-0577-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Purpose of Review This manuscript aims to review the cutting-edge developments regarding to the diagnosis, management, and prevention of leprosy in children. Recent Findings Leprosy transmission still occurs continuously in some endemic areas in the world. Leprosy in children below 15 years old is a robust indicator of active source of infection in the community where they live. A special focus on children to reduce disabilities and reduce transmission is one of the core areas of interventions of the global leprosy strategy 2016-2020. Ongoing research is trying to develop better diagnostic tests and to advance chemoprophylaxis and immunoprophylaxis approaches. Summary Early diagnosis in children can be hard because of the wide range of clinical aspects of the skin lesions and mainly due to the difficulty of performing the clinical peripheral nerve evaluation. We must maintain leprosy expertise and improve the health professionals training for leprosy diagnosis, since we still have a long journey to reach leprosy elimination.

引用

页数：8

共 46 条

[41]

Villarroel MF, 2007, LEPROSY REV, V78, P102

[42]

WHO, 2017, WHO MULT THER MDT

[43]

WHO, 2017, DIAGN OF LEPR

[44]

Yan LB, 2015, LEPROSY REV, V86, P75

[45] Review of thalidomide use in the pediatric population [J].

Yang, Catherine S. ;

Kim, Changhyun ;

Antaya, Richard J. .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2015, 72 (04) :703-711

[46]

,, 2016, Weekly Epidemiological Record, V91, P405

← 1 2 3 4 5 →