Green novel multicomponent synthesis and biological evaluation of new oxazolopyrazoloazepines and reduction of nitrophenols in the presence of Ag/Fe3O4/ZnO@MWCNT MNCs

被引：6

作者：

Savari, Mehdi ^{[1
]}

Varasteh-Moradi, Ali ^{[1
]}

Sayyed-Alangi, S. Zahra ^{[2
]}

Hossaini, Zinatossadat ^{[3
]}

Mehrabian, Ramin Zafar ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Gorgan Branch, Gorgan, Golestan, Iran

[2] Islamic Azad Univ, Dept Chem, Azadshahr Branch, Azadshahr, Iran

[3] Islamic Azad Univ, Dept Chem, Qaemshahr Branch, Qaemshahr, Iran

来源：

MOLECULAR DIVERSITY | 2022年 / 26卷 / 06期

关键词：

Ag/Fe3O4/ZnO@MWCNT MNCs; Oxazolopyrazoloazepines; Multicomponent reaction; Alkyl bromide; Anilines; Oxalylchloride; ONE-POT SYNTHESIS; DOMINO REACTIONS; EFFICIENT SYNTHESIS; NATURAL-PRODUCTS; GROUND-STATES; ORGANIC-DYES; AERIAL PART; AB-INITIO; NANOPARTICLES; DERIVATIVES;

D O I：

10.1007/s11030-022-10390-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this research, new derivatives of oxazolopyrazoloazepines were synthesized in high yields using multicomponent reaction of anilines, oxalylchloride, alkyl bromides, activated acetylenic compounds, hydrazine and ethyl bromopyruvate in the presence of Ag/Fe3O4/ZnO@@MWCNT magnetic nanocomposite (MNCs) as a high-performance magnetic catalyst in ionic liquid at room temperature. The Ag/Fe3O4/ZnO@@MWCNT magnetic nanocomposites (MNCs) were synthesized using 1-octhyl-3-methyl imidazolium bromide ([OMIM]Br) as a stabilizer and soft template. Also, the catalytic activity of the Ag/Fe3O4/ZnO@MWCNT MNCs was evaluated in reduction of organic pollutants such as 4-nitrophenol (4-NP) in water at mild conditions. The results indicated that the biosynthesized nanocomposites (NCs) have high catalytic activity for organic pollutants within few seconds. Because of having benzazepine nucleus in the synthesized compounds, we investigate antioxidant property of some synthesized oxazolopyrazoloazepines by diphenyl-picrylhydrazine radical trapping and power of ferric reduction experiment. Short time of reaction, high yields of product, easy separation of catalyst and products are some advantages of this procedure. [GRAPHICS] .

引用

页码：3279 / 3294

页数：16

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