Gold nanoparticles as a label-free probe for the detection of amyloidogenic protein

被引：20

作者：

Zhang, Hai-Jie ^{[1
]}

Zheng, Hu-Zhi ^{[1
]}

Long, Yi-Juan ^{[1
]}

Xiao, Geng-Fu ^{[2
]}

Zhang, Ling-Yan ^{[1
]}

Wang, Qin-Long ^{[1
]}

Gao, Mei ^{[1
]}

Bai, Wen-Jun ^{[1
]}

机构：

[1] Southwest Univ, Coll Chem & Chem Engn, Chongqing 400715, Peoples R China

[2] Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430071, Peoples R China

来源：

TALANTA | 2012年 / 89卷

基金：

中国国家自然科学基金;

关键词：

Amyloidogenic protein; Gold nanoparticle; Prion protein; Label-free detection; CREUTZFELDT-JAKOB-DISEASE; PRION PROTEIN; CAPILLARY-ELECTROPHORESIS; COLORIMETRIC DETECTION; CEREBROSPINAL-FLUID; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; ALPHA-SYNUCLEIN; QUANTUM DOTS; BLOOD;

D O I：

10.1016/j.talanta.2011.12.052

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Because amyloidogenic proteins, such as prion protein, beta-amyloid peptide and alpha-synuclein, are associated with a variety of diseases, methods for their detection are important. Recombinant prion protein (rPrP) can selectively induce aggregation of dihydrolipoic acid capped gold nanoparticles (DHLA-AuNPs), which reduces the absorbance of the DHLA-AuNPs and changes their color from red to blue. These changes were used for label-free qualitative and quantitative detection of amyloidogenic protein. The addition of NaCl improved the detection sensitivity considerably, and the detection limit was as low as 33 pmol/L. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：401 / 406

页数：6

共 50 条

[41] A label-free immunosensor by controlled fabrication of monoclonal antibodies and gold nanoparticles inside the mesopores
Lin, Jiehua
Wei, Zhijing
Chu, Pengfei
ANALYTICAL BIOCHEMISTRY, 2012, 421 (01) : 97 - 102
[42] An ultrasensitive method for the detection of gene fragment from transgenics using label-free gold nanoparticle probe and dynamic light scattering
Gao, Duyang
Sheng, Zonghai
Han, Heyou
ANALYTICA CHIMICA ACTA, 2011, 696 (1-2) : 1 - 5
[43] A label-free electrochemical biosensor for microRNA detection based on apoferritin-encapsulated Cu nanoparticles
Wang, Mo
Yin, Huanshun
Fu, Zhengliang
Guo, Yunlong
Wang, Xinxu
Zhou, Yunlei
Ai, Shiyun
JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 2014, 18 (10) : 2829 - 2835
[44] Controlled assembly of peptide-functionalized gold nanoparticles for label-free detection of blood coagulation Factor XIII activity
Chandrawati, Rona
Stevens, Molly M.
CHEMICAL COMMUNICATIONS, 2014, 50 (41) : 5431 - 5434
[45] The comparison between label-free and non-cross-linking methods with gold nanoparticles for colorimetric detection of Paracoccidioides brasiliensis
Cândido M.A.
Comparato-Filho O.O.
Oliveira I.R.
Castilho M.L.
Raniero L.
Research on Biomedical Engineering, 2019, 35 (01) : 39 - 44
[46] Label-free Colorimetric Assay Based on Gold Nanoparticles in Detection of NOS1AP with Single Nucleotide Polymorphism
Guo Qing-Chuan
Wang Xiang
Lou Xin-Hui
Mao Hong-Ju
Jia Jie
Jin Qing-Hui
Zhao Jian-Long
Zhang Feng
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2010, 31 (10): : 1965 - 1969
[47] Rolling circle amplification triggered poly adenine-gold nanoparticles production for label-free electrochemical detection of thrombin
Fan, Taotao
Du, Yan
Yao, Yao
Wu, Jing
Meng, Si
Luo, Jianjun
Zhang, Xing
Yang, Dongzhi
Wang, Chunyan
Qian, Yong
Gao, Fenglei
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 266 : 9 - 18
[48] Label-Free Aptasensors for the Detection of Mycotoxins
Rhouati, Amina
Catanante, Gaelle
Nunes, Gilvanda
Hayat, Akhtar
Marty, Jean-Louis
SENSORS, 2016, 16 (12):
[49] Label-free protein and pathogen detection using the atomic force microscope
Huff, JL
Lynch, MP
Nettikadan, S
Johnson, JC
Vengasandra, S
Henderson, E
JOURNAL OF BIOMOLECULAR SCREENING, 2004, 9 (06) : 491 - 497
[50] Label-free and enzyme-free one-step rapid colorimetric detection of DNA methylation based on unmodified gold nanoparticles
Li, Zhi-Mei
Pi, Ting
Yan, Xi-Luan
Tang, Xiao-Meng
Deng, Rui-Hong
Zheng, Xiang-Juan
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2020, 238 (238)

← 1 2 3 4 5 →