An overview on atopic dermatitis in children

被引：0

作者：

Susac, Andrei ^{[3
]}

Babic, Sanja ^{[3
]}

Lipozencic, Jasna ^{[1
,2
]}

机构：

[1] Univ Zagreb, Ctr Hosp, Univ Dept Dermatol & Venereol, HR-10000 Zagreb, Croatia

[2] Univ Zagreb, Sch Med, Zagreb 41001, Croatia

[3] Matul Polyclin, Split, Croatia

来源：

ACTA DERMATOVENEROLOGICA CROATICA | 2007年 / 15卷 / 03期

关键词：

atopic dermatitis; children; etiology; pathophysiology; clinical evaluation; diagnosis; treatment;

D O I：

暂无

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Atopic dermatitis (AD) is a chronic recurring inflammatory skin disease divided into at least two different forms: atopic (extrinsic) and non-atopic (intrinsic) dermatitis. Genetic epidemiological studies have unraveled several chromosomal loci with putative candidate genes, some of which are localized on chromosomes 3, 17 and 20, and most recently on 1q21. AD represents a large and continuous spectrum of one disease where different contributions from epidermal, immunologically relevant genes and their interactions with environmental signals dictate the outcome of sensitization. AD appears early in childhood and has a typical clinical picture with characteristic remissions and exacerbations, The variability of the clinical picture is related to the complex etiopathogenesis of the disease and patient's age, and is accompanied by moderate to strong itch. This review outlines recent standpoints on the etiopathogenesis, diagnosis, treatment and prevention of AD.

引用

页码：158 / 166

页数：9

共 69 条

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