Effects of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia

被引：52
作者：
Humma, LM
Puckett, BJ
Richardson, HE
Terra, SG
Andrisin, TE
Lejeune, BL
Wallace, MR
Lewis, JF
McNamara, DM
Picoult-Newberg, L
Pepine, CJ
Johnson, JA
机构：
[1] Univ Florida, Dept Pharm, Gainesville, FL 32608 USA
[2] Univ Florida, Dept Med, Gainesville, FL 32608 USA
[3] Univ Pittsburgh, Med Ctr, Cardiovasc Inst, Pittsburgh, PA USA
[4] Orchid Biosci Inc, Princeton, NJ USA
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 2001年 / 88卷 / 09期
关键词：
D O I：
10.1016/S0002-9149(01)01986-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A significant association between beta (1)-adrenergic receptor codon 389 genotype and various hemodynamic parameters is reported for a population with symptoms of ischemic heart disease or other clinical indications for cardiovascular stress testing. This finding may have important implications with respect to cardiovascular disease and the efficacy of beta blockers, in cardiovascular disease.
引用
收藏
页码：1034 / +
页数：5
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