Hepatic Encephalopathy and Health-Related Quality of Life

被引:30
作者
Bianchi, Giampaolo [1 ]
Giovagnoli, Marco [1 ]
Sasdelli, Anna Simona [1 ]
Marchesini, Giulio [1 ]
机构
[1] Alma Mater Studiorum Univ Bologna, Dept Med & Surg, S Orsola Malpighi Hosp, I-40138 Bologna, Italy
关键词
Health status; Hepatic encephalopathy; Liver cirrhosis; Depression; PORTAL-SYSTEMIC ENCEPHALOPATHY; CHRONIC LIVER-DISEASE; SLEEP DISTURBANCE; NEUROPSYCHOLOGICAL TESTS; WORKING PARTY; FINAL REPORT; CIRRHOSIS; DIAGNOSIS; RECOMMENDATIONS; QUESTIONNAIRE;
D O I
10.1016/j.cld.2011.12.003
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The impact of overt hepatic encephalopathy on health-related quality of life is well defined, but it remains to be demonstrated how much the presence of minimal hepatic encephalopathy (MHE) might impair patients' perceived health status. MHE reduces cognitive abilities, with specific impairment in manual abilities, which can lead to a depressed mood that impairs perceived health status. Therefore, all subjects with cirrhosis should be systematically screened for MHE by validated tools. Early detection and treatment is mandatory to improve the quality of life of patients with advanced cirrhosis, their social isolation, and their daily lives.
引用
收藏
页码:159 / +
页数:14
相关论文
共 52 条
[1]  
Aaronson N.K., 1998, Oncology, V2, P69
[2]   Clinical features and survivial of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric tests [J].
Amodio, P ;
Del Piccolo, F ;
Marchetti, P ;
Angeli, P ;
Iemmolo, R ;
Caregaro, L ;
Merkel, C ;
Gerunda, G ;
Gatta, A .
HEPATOLOGY, 1999, 29 (06) :1662-1667
[3]   Health related quality of life and minimal hepatic encephalopathy. It is time to insert 'quality' in health care [J].
Amodio, Piero .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2009, 24 (03) :329-330
[4]   Health-related quality of life (HR-QOL) and regulatory issues - An assessment of the European Agency for the Evaluation of Medicinal Products (EMEA) recommendations on the use of HR-QOL measures in drug approval [J].
Apolone, G ;
De Carli, G ;
Brunetti, M ;
Garattini, S .
PHARMACOECONOMICS, 2001, 19 (02) :187-195
[5]   Influence of hepatic encephalopathy on health-related quality of life in patients with cirrhosis [J].
Arguedas, MR ;
DeLawrence, TG ;
McGuire, BM .
DIGESTIVE DISEASES AND SCIENCES, 2003, 48 (08) :1622-1626
[6]   Probiotic yogurt for the treatment of minimal hepatic encephalopathy [J].
Bajaj, Jasmohan S. ;
Saeian, Kia ;
Christensen, Kenneth M. ;
Hafeezullah, Muhammad ;
Varma, Rajiv R. ;
Franco, Jose ;
Pleuss, Joan A. ;
Krakower, Glenn ;
Hoffmann, Raymond G. ;
Binion, David G. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2008, 103 (07) :1707-1715
[7]   Minimal hepatic encephalopathy matters in daily life [J].
Bajaj, Jasmohan S. .
WORLD JOURNAL OF GASTROENTEROLOGY, 2008, 14 (23) :3609-3615
[8]   Assessment of health-related quality of life in Chinese patients with minimal hepatic encephalopathy [J].
Bao, Zhi-Jun ;
Qiu, De-Kai ;
Ma, Xiong ;
Fan, Zhu-Ping ;
Zhang, Gan-Sheng ;
Huang, Yi-Qin ;
Yu, Xiao-Feng ;
Zeng, Min-De .
WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (21) :3003-3008
[9]   THE SICKNESS IMPACT PROFILE - DEVELOPMENT AND FINAL REVISION OF A HEALTH-STATUS MEASURE [J].
BERGNER, M ;
BOBBITT, RA ;
CARTER, WB ;
GILSON, BS .
MEDICAL CARE, 1981, 19 (08) :787-805
[10]   Psychological status and depression in patients with liver cirrhosis [J].
Bianchi, G ;
Marchesini, G ;
Nicolino, F ;
Graziani, R ;
Sgarbi, D ;
Loguercio, C ;
Abbiati, R ;
Zoli, M .
DIGESTIVE AND LIVER DISEASE, 2005, 37 (08) :593-600