A selective fluorescent turn-on NIR probe for cysteine

被引：98
作者：
Jiang, Xin-Dong [1 ]
Zhang, Jian [1 ]
Shao, Xiangmin [1 ]
Zhao, Weili [1 ,2 ]
机构：
[1] Henan Univ, Minist Educ, Key Lab Special Funct Mat, Kaifeng 475004, Henan, Peoples R China
[2] Fudan Univ, Sch Pharm, Shanghai 201203, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 10期
基金：
中国国家自然科学基金;
关键词：
RESTRICTED AZA-BODIPY; HIGHLY FLUORESCENT; HOMOCYSTEINE; RECOGNITION; THIOLS; CYSTEINE/HOMOCYSTEINE; QUANTIFICATION; CHEMOSENSOR; GLUTATHIONE; SENSORS;
D O I：
10.1039/c2ob07046d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A selective and sensitive turn-on fluorescent NIR probe for cysteine has been developed. Cleavage of 2,4-dinitrobenzene-sulfonyl (DNBS) with thiols switches the weakly fluorescent aza-BODIPY dye (lambda(em) = 734 nm, Phi(f) = 0.03) to a strongly fluorescent species in the NIR region (lambda(em) = 755 nm, Phi(f) = 0.14).
引用
收藏
页码：1966 / 1968
页数：3
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