AUTOMATED BRAIN EXTRACTION USING MULTI-ATLAS PROPAGATION AND SEGMENTATION (MAPS)

被引：0

作者：

Leung, Kelvin K. ^{[1
,2
]}

Barnes, Josephine ^{[1
]}

Modat, Marc ^{[1
]}

Ridgway, Gerard R. ^{[1
,2
]}

Bartlett, Jonathan W. ^{[3
]}

Fox, Nick C. ^{[1
]}

Ourselin, Sebastien ^{[1
,2
]}

机构：

[1] UCL Inst Neurol, Dementia Res Ctr, Queen Sq, London, England

[2] UCL, Ctr Med Imag Comp, Dept Med Phys & Bioengn, London WC1E 6BT, England

[3] London Sch Hygiene & Trop Med, Dept Med Statist, London, England

来源：

2011 8TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO | 2011年

基金：

英国医学研究理事会;

关键词：

Automated brain extraction; BET; BSE; HWA; MAPS; IMAGES; MRI; ALGORITHMS; MODEL;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Whole brain extraction is an important pre-processing step in neuroimage analysis. We compared the accuracy of four automated brain extraction methods: Brain Extraction Tool (BET), Brain Surface Extractor (BSE), Hybrid Watershed Algorithm (HWA) and a Multi-Atlas Propagation and Segmentation (MAPS) technique we have previously developed for hippocampal segmentation. The four methods were applied to extract whole brains from 682 1.5T and 157 3T T-1-weighted MR baseline images from the Alzheimer's Disease Neuroimaging Initiative database. Using semi-automated brain segmentations with manual editing and checking as the gold-standard, the median (1st-99th centile range) Jaccard indices of MAPS, HWA, BET and BSE were 0.981 (0.041), 0.970 (0.126), 0.969 (0.826) and 0.953 (0.217) in 1.5T scans, and 0.980 (0.047), 0.962 (0.701), 0.965 (0.731) and 0.900 (0.550) in 3T scans. In conclusion, MAPS had relatively high accuracy and low variability compared to HWA, BET and BSE in MR scans with and without atrophy.

引用

页码：2053 / 2056

页数：4

共 19 条

[1] Multi-atlas based segmentation of brain images: Atlas selection and its effect on accuracy [J].

Aljabar, P. ;

Heckemann, R. A. ;

Hammers, A. ;

Hajnal, J. V. ;

Rueckert, D. .

NEUROIMAGE, 2009, 46 (03) :726-738

[2] Unified segmentation [J].

Ashburner, J ;

Friston, KJ .

NEUROIMAGE, 2005, 26 (03) :839-851

[3] Quantitative comparison of four brain extraction algorithms [J].

Boesen, K ;

Rehm, K ;

Schaper, K ;

Stoltzner, S ;

Woods, R ;

Lüders, E ;

Rottenberg, D .

NEUROIMAGE, 2004, 22 (03) :1255-1261

[4] Quantitative evaluation of automated skull-stripping methods applied to contemporary and legacy images: Effects of diagnosis, bias correction, and slice location [J].

Fennema-Notestine, C ;

Ozyurt, IB ;

Clark, CP ;

Morris, S ;

Bischoff-Grethe, A ;

Bondi, MW ;

Jernigan, TL ;

Fischl, B ;

Segonne, F ;

Shattuck, DW ;

Leahy, RM ;

Rex, DE ;

Toga, AW ;

Zou, KH ;

Birn, M ;

Brown, GG .

HUMAN BRAIN MAPPING, 2006, 27 (02) :99-113

[5] Interactive algorithms for the segmentation and quantitation of 3-D MRI brain scans [J].

Freeborough, PA ;

Fox, NC ;

Kitney, RI .

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 1997, 53 (01) :15-25

[6] Automatic anatomical brain MRI segmentation combining label propagation and decision fusion [J].

Heckemann, Rolf A. ;

Hajnal, Joseph V. ;

Aljabar, Paul ;

Rueckert, Daniel ;

Hammers, Alexander .

NEUROIMAGE, 2006, 33 (01) :115-126

[7] Automated cross-sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease [J].

Leung, Kelvin K. ;

Barnes, Josephine ;

Ridgway, Gerard R. ;

Bartlett, Jonathan W. ;

Clarkson, Matthew J. ;

Macdonald, Kate ;

Schuff, Norbert ;

Fox, Nick C. ;

Ourselin, Sebastien .

NEUROIMAGE, 2010, 51 (04) :1345-1359

[8] Fast free-form deformation using graphics processing units [J].

Modat, Marc ;

Ridgway, Gerard R. ;

Taylor, Zeike A. ;

Lehmann, Manja ;

Barnes, Josephine ;

Hawkes, David J. ;

Fox, Nick C. ;

Ourselin, Sebastien .

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2010, 98 (03) :278-284

[9] Shape-based averaging [J].

Rohlfing, Torsten ;

Maurer, Calvin R., Jr. .

IEEE TRANSACTIONS ON IMAGE PROCESSING, 2007, 16 (01) :153-161

[10] Nonrigid registration using free-form deformations: Application to breast MR images [J].

Rueckert, D ;

Sonoda, LI ;

Hayes, C ;

Hill, DLG ;

Leach, MO ;

Hawkes, DJ .

IEEE TRANSACTIONS ON MEDICAL IMAGING, 1999, 18 (08) :712-721

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