The endocytic pathway: A mosaic of domains

被引:559
作者
Gruenberg, J [1 ]
机构
[1] Univ Geneva, Dept Biochem, CH-1211 Geneva 4, Switzerland
关键词
D O I
10.1038/35096054
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Organelles in the endocytic pathway are composed of a mosaic of structural and functional regions. These regions consist, at least in part, of specialized protein-lipid domains within the plane of the membrane, or of protein complexes associated with specific membrane lipids. Whereas some of these molecular assemblies can be found in more than one compartment, a given combination seems to be unique to each compartment, indicating that membrane organization might be modular.
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收藏
页码:721 / 730
页数:10
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