APPLICATIONS OF NEXT-GENERATION SEQUENCING Towards a genomics-informed, real-time, global pathogen surveillance system

被引:414
作者
Gardy, Jennifer L. [1 ,2 ]
Loman, Nicholas J. [3 ]
机构
[1] British Columbia Ctr Dis Control, Vancouver, BC V5Z 4R4, Canada
[2] Univ British Columbia, Schl Populat & Publ Hlth, Vancouver, BC V6T 1Z3, Canada
[3] Univ Birmingham, Inst Microbiol & Infect, Birmingham B15 2TT, W Midlands, England
关键词
DIGITAL DISEASE DETECTION; ZIKA VIRUS; SYNDROMIC SURVEILLANCE; INFECTIOUS-DISEASE; OUTBREAK DETECTION; ZOONOTIC VIRUSES; PUBLIC-HEALTH; EBOLA; TRANSMISSION; EPIDEMIOLOGY;
D O I
10.1038/nrg.2017.88
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable sequencing of pathogen genomes - now a staple of the public health microbiology laboratory in well-resourced settings - can affect each of these areas. Coupling genomic diagnostics and epidemiology to innovative digital disease detection platforms raises the possibility of an open, global, digital pathogen surveillance system. When informed by a One Health approach, in which human, animal and environmental health are considered together, such a genomics-based system has profound potential to improve public health in settings lacking robust laboratory capacity.
引用
收藏
页码:9 / 20
页数:12
相关论文
共 121 条
[1]   Traditional and syndromic surveillance of infectious diseases and pathogens [J].
Abat, Cedric ;
Chaudet, Herve ;
Rolain, Jean-Marc ;
Colson, Philippe ;
Raoult, Didier .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2016, 48 :22-28
[2]  
[Anonymous], PLOS CURR
[3]   Non-random patterns in viral diversity [J].
Anthony, Simon J. ;
Islam, Ariful ;
Johnson, Christine ;
Navarrete-Macias, Isamara ;
Liang, Eliza ;
Jain, Komal ;
Hitchens, Peta L. ;
Che, Xiaoyu ;
Soloyvov, Alexander ;
Hicks, Allison L. ;
Ojeda-Flores, Rafael ;
Zambrana-Torrelio, Carlos ;
Ulrich, Werner ;
Rostal, Melinda K. ;
Petrosov, Alexandra ;
Garcia, Joel ;
Haider, Najmul ;
Wolfe, Nathan ;
Goldstein, Tracey ;
Morse, Stephen S. ;
Rahman, Mahmudur ;
Epstein, Jonathan H. ;
Mazet, Jonna K. ;
Daszak, Peter ;
Lipkin, W. Ian .
NATURE COMMUNICATIONS, 2015, 6
[4]   A Strategy To Estimate Unknown Viral Diversity in Mammals [J].
Anthony, Simon J. ;
Epstein, Jonathan H. ;
Murray, Kris A. ;
Navarrete-Macias, Isamara ;
Zambrana-Torrelio, Carlos M. ;
Solovyov, Alexander ;
Ojeda-Flores, Rafael ;
Arrigo, Nicole C. ;
Islam, Ariful ;
Khan, Shahneaz Ali ;
Hosseini, Parviez ;
Bogich, Tiffany L. ;
Olival, Kevin J. ;
Sanchez-Leon, Maria D. ;
Karesh, William B. ;
Goldstein, Tracey ;
Luby, Stephen P. ;
Morse, Stephen S. ;
Mazet, Jonna A. K. ;
Daszak, Peter ;
Lipkin, W. Ian .
MBIO, 2013, 4 (05)
[5]   The Reliability of Tweets as a Supplementary Method of Seasonal Influenza Surveillance [J].
Aslam, Anoshe A. ;
Tsou, Ming-Hsiang ;
Spitzberg, Brian H. ;
An, Li ;
Gawron, J. Mark ;
Gupta, Dipak K. ;
Peddecord, K. Michael ;
Nagel, Anna C. ;
Allen, Christopher ;
Yang, Jiue-An ;
Lindsay, Suzanne .
JOURNAL OF MEDICAL INTERNET RESEARCH, 2014, 16 (11)
[6]   Emerging Concepts of Data Integration in Pathogen Phylodynamics [J].
Baele, Guy ;
Suchard, Marc A. ;
Rambaut, Andrew ;
Lemey, Philippe .
SYSTEMATIC BIOLOGY, 2017, 66 (01) :E47-E65
[7]   Emergence of Zaire Ebola Virus Disease in Guinea [J].
Baize, Sylvain ;
Pannetier, Delphine ;
Oestereich, Lisa ;
Rieger, Toni ;
Koivogui, Lamine ;
Magassouba, N'Faly ;
Soropogui, Barre ;
Sow, Mamadou Saliou ;
Keita, Sakoba ;
De Clerck, Hilde ;
Tiffany, Amanda ;
Dominguez, Gemma ;
Loua, Mathieu ;
Traore, Alexis ;
Kolie, Moussa ;
Malano, Emmanuel Roland ;
Heleze, Emmanuel ;
Bocquin, Anne ;
Mely, Stephane ;
Raoul, Herve ;
Caro, Valerie ;
Cadar, Daniel ;
Gabriel, Martin ;
Pahlmann, Meike ;
Tappe, Dennis ;
Schmidt-Chanasit, Jonas ;
Impouma, Benido ;
Diallo, Abdoul Karim ;
Formenty, Pierre ;
Van Herp, Michel ;
Guenther, Stephan .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (15) :1418-1425
[8]  
Birko S., PLOS ONE, V10
[9]   Reduced evolutionary rate in reemerged Ebola virus transmission chains [J].
Blackley, David J. ;
Wiley, Michael R. ;
Ladner, Jason T. ;
Fallah, Mosoka ;
Lo, Terrence ;
Gilbert, Merle L. ;
Gregory, Christopher ;
D'ambrozio, Jonathan ;
Coulter, Stewart ;
Mate, Suzanne ;
Balogun, Zephaniah ;
Kugelman, Jeffrey ;
Nwachukwu, William ;
Prieto, Karla ;
Yeiah, Adolphus ;
Amegashie, Fred ;
Kearney, Brian ;
Wisniewski, Meagan ;
Saindon, John ;
Schroth, Gary ;
Fakoli, Lawrence ;
Diclaro, Joseph W., II ;
Kuhn, Jens H. ;
Hensley, Lisa E. ;
Jahrling, Peter B. ;
Stroher, Ute ;
Nichol, Stuart T. ;
Massaquoi, Moses ;
Kateh, Francis ;
Clement, Peter ;
Gasasira, Alex ;
Bolay, Fatorma ;
Monroe, Stephan S. ;
Rambaut, Andrew ;
Sanchez-Lockhart, Mariano ;
Laney, A. Scott ;
Nyenswah, Tolbert ;
Christie, Athalia ;
Palacios, Gustavo .
SCIENCE ADVANCES, 2016, 2 (04)
[10]   Preventing Pandemics Via International Development: A Systems Approach [J].
Bogich, Tiffany L. ;
Chunara, Rumi ;
Scales, David ;
Chan, Emily ;
Pinheiro, Laura C. ;
Chmura, Aleksei A. ;
Carroll, Dennis ;
Daszak, Peter ;
Brownstein, John S. .
PLOS MEDICINE, 2012, 9 (12)