Recent progress on the diagnosis of 2019 Novel Coronavirus

被引：52

作者：

Ren, Linzhu ^{[1
]}

Li, Chun ^{[2
]}

机构：

[1] Jilin Univ, Coll Anim Sci, Changchun 130062, Peoples R China

[2] Chinese Peoples Liberat Army 964 Hosp, Changchun, Peoples R China

来源：

TRANSBOUNDARY AND EMERGING DISEASES | 2020年 / 67卷 / 04期

基金：

中国国家自然科学基金;

关键词：

antibody; clustered regularly interspaced short palindromic repeats (CRISPR); Corona Virus Disease 2019 (COVID-19); detection; real-time RT-PCR; reverse transcription loop-mediated isothermal amplification (RT-LAMP); severe acute respiratory syndrome coronavirus 2 (2019 Novel Coronavirus SARS-CoV-2); COVID-19; EVOLUTION;

D O I：

10.1111/tbed.13620

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic. Therefore, convenient, timely and accurate detection of SARS-CoV-2 is urgently needed. Here, we review the types, characteristics and shortcomings of various detection methods, as well as perspectives for the SARS-CoV-2 diagnosis. Clinically, nucleic acid-based methods are sensitive but prone to false-positive. The antibody-based method has slightly lower sensitivity but higher accuracy. Therefore, it is suggested to combine the two methods to improve the detection accuracy of COVID-19.

引用

页码：1485 / 1491

页数：7

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