PEG-600: a facile and eco-friendly reaction medium for the synthesis of N-alkyl derivatives of indole-3-carboxyaldehyde

被引:20
作者
Dubey, P. K. [1 ]
Venkatanarayana, M. [1 ]
机构
[1] JNTUH Coll Engn, Dept Chem, Hyderabad 500085, Andhra Pradesh, India
关键词
Indole-3-aldehyde; PEG-600; alkylation; INDOLE-3-ALDEHYDES; EFFICIENT;
D O I
10.1080/17518251003749379
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A facile and eco-friendly methodology for the synthesis of N-alkyl/aralkyl derivatives of indole & indole-3-carboxyaldehydes mediated by polyethylene glycol as an efficient and green solvent is described.
引用
收藏
页码:257 / 261
页数:5
相关论文
共 16 条
[1]   Uncatalyzed Knoevenagel condensation in PEG-600 at room temperature [J].
Bandgar, Babasaheb P. ;
Korbad, Balaji L. ;
Patil, Sachin A. ;
Bandgar, Sunita B. ;
Chavan, Hemant V. ;
Hote, Baliram S. .
AUSTRALIAN JOURNAL OF CHEMISTRY, 2008, 61 (09) :700-703
[2]   FORMYLATION AND CYANOETHYLATION OF SUBSTITUTED INDOLES [J].
BLUME, RC ;
LINDWALL, HG .
JOURNAL OF ORGANIC CHEMISTRY, 1945, 10 (03) :255-258
[3]  
CHAUHAN PMS, 1994, INDIAN J CHEM B, V33, P32
[4]   142 Preparation of certain 3-substituted Indoles [J].
Cornforth, RH ;
Robinson, R .
JOURNAL OF THE CHEMICAL SOCIETY, 1942, :680-682
[5]   NITRATION OF SOME METHYL SUBSTITUTED INDOLE-3-ALDEHYDES IN SULPHURIC ACID [J].
DASETTIM.A ;
SAETTONE, MF .
TETRAHEDRON, 1965, 21 (08) :1923-&
[6]  
Dicekerson T J, 2002, CHEM REV, V102, P3325
[7]  
Dubey PK, 2006, INDIAN J HETEROCY CH, V15, P205
[8]  
James P.N., 1959, ORG SYNTH, V39, P30, DOI [10.15227/orgsyn.039.0030, DOI 10.15227/ORGSYN.039.0030]
[9]   A simple and green procedure for the conjugate addition of thiols to conjugated alkenes employing polyethylene glycol (PEG) as an efficient recyclable medium [J].
Kamal, A ;
Reddy, DR ;
Rajendar .
TETRAHEDRON LETTERS, 2005, 46 (46) :7951-7953
[10]   An efficient method for Knoevenagel condensation: a facile synthesis of 5-arylidenyl 2,4-thiazolidinedione [J].
Mahalle, Shital R. ;
Netankar, Prashant D. ;
Bondge, Sandipan P. ;
Mane, Ramrao A. .
GREEN CHEMISTRY LETTERS AND REVIEWS, 2008, 1 (02) :103-106