Phosphine-Free Palladium-Catalyzed Direct Bisarylation of Pyrroles with Aryl Iodides on Water

被引：23

作者：

Cho, Beom Shin ^{[1
]}

Bae, Hyun Jung ^{[1
]}

Chung, Young Keun ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Nat Sci, Dept Chem, Seoul 151747, South Korea

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 10期

基金：

新加坡国家研究基金会;

关键词：

METALATION-DEPROTONATION MECHANISM; H BOND FUNCTIONALIZATION; DIRECT ARYLATION; ROOM-TEMPERATURE; BROMIDES; ACTIVATION; REACTIVITY; CHLORIDES; HALIDES; ALKYNES;

D O I：

10.1021/acs.joc.5b00451

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Pd-catalyzed bisarylation of pyrroles with aryl iodides on water is described. The reaction proceeds under mild reaction conditions, i.e., relatively low temperature (40 degrees C) and phosphine-free.

引用

页码：5302 / 5307

页数：6

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