Dark Chocolate and Blood Pressure: A Novel Study from Jordan

被引:0
作者
Al-Safi, Saafan A. [2 ]
Ayoub, Nehad M. [2 ]
Al-Doghim, Imad [3 ]
Aboul-Enein, Faisal H. [1 ]
机构
[1] Walden Univ, Coll Hlth Sci, Sch Nursing, Minneapolis, MN 55401 USA
[2] Jordan Univ Sci & Technol, Fac Pharm, Dept Clin Pharm, Irbid 22110, Jordan
[3] King Hussein Med Ctr, Amman, Jordan
关键词
Dark chocolate; blood pressure; heart rate; flavonoids; Jordan; FLAVANOL-RICH COCOA; DEPENDENT VASODILATION; CARDIOVASCULAR HEALTH; ENDOTHELIAL FUNCTION; NITRIC-OXIDE; RISK-FACTORS;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Aim: The goal of this study was to assess the effect of dark chocolate intake on cardiovascular parameters like blood pressure and heart rate values in a normotensive population. Subjects and methods: This is a randomized cross-sectional study involving a total of 14,310 adults that were selected from various regions of Jordan. Well-trained pharmacy students interviewed participants in the outpatient settings. Participants reported their weekly intake of dark chocolate that has been further classified into mild (1-2 bars/week), moderate (3-4 bars/week), and high intake (>4 bars/week). For each participant, the systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate were measured three times with (10-15) minute intervals in the sitting position and the resting state. The arterial blood pressure (ABP) was calculated from the measured SBP and DBP values. Results: All measured blood pressure values were significantly decreased for participants who reported higher dark chocolate consumption. Our results showed that heart rate values were not affected by variable intake of dark chocolate. In addition, increasing dark chocolate intake was associated with a significant decrease of blood pressure values in participants irrespective of the family history of hypertension or the age of the individual. However, heart rate values were unaffected. Conclusion: Higher intake of dark chocolate can be associated with lower values of blood pressure, while its effect on heart rate values was not consistent.
引用
收藏
页码:595 / 599
页数:5
相关论文
共 19 条
[1]   Inhibition of angiotensin converting enzyme activity by flavanol-rich foods [J].
Actis-Goretta, L ;
Ottaviani, JI ;
Fraga, CG .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (01) :229-234
[2]   Daily consumption of a dark chocolate containing flavanols and added sterol esters affects cardiovascular risk factors in a normotensive population with elevated cholesterol [J].
Allen, Robin R. ;
Carson, LeaAnn ;
Kwik-Uribe, Catherine ;
Evans, Ellen M. ;
Erdman, John W., Jr. .
JOURNAL OF NUTRITION, 2008, 138 (04) :725-731
[3]   Cocoa intake, blood pressure, and cardiovascular mortality - The Zutphen Elderly Study [J].
Buijsse, B ;
Feskens, EJM ;
Kok, FJ ;
Kromhout, D .
ARCHIVES OF INTERNAL MEDICINE, 2006, 166 (04) :411-417
[4]   A double-blind, placebo-controlled, randomized trial of the effects of dark chocolate and cocoa on variables associated with neuropsychological functioning and cardiovascular health: clinical findings from a sample of healthy, cognitively intact older adults [J].
Crews, W. David, Jr. ;
Harrison, David W. ;
Wright, James W. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2008, 87 (04) :872-880
[5]   Chocolate and prevention of cardiovascular disease: A systematic review [J].
Ding, Eric L. ;
Hutfless, Susan M. ;
Ding, Xin ;
Girotra, Saket .
NUTRITION & METABOLISM, 2006, 3 (1)
[6]   Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults [J].
Engler, MB ;
Engler, MM ;
Chen, CY ;
Malloy, MJ ;
Browne, A ;
Chiu, EY ;
Kwak, HK ;
Milbury, P ;
Paul, SM ;
Blumberg, J ;
Mietus-Synder, ML .
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2004, 23 (03) :197-204
[7]  
Engler MB, 2006, NUTR REV, V64, P109, DOI 10.1111/j.1753-4887.2006.tb00194.x
[8]  
Erdman JW, 2008, ASIA PAC J CLIN NUTR, V17, P284
[9]   Acute dark chocolate and cocoa ingestion and endothelial function: a randomized controlled crossover trial [J].
Faridi, Zubaida ;
Njike, Valentine Yanchou ;
Dutta, Suparna ;
Ali, Ather ;
Katz, David L. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2008, 88 (01) :58-63
[10]   Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans [J].
Fisher, NDL ;
Hughes, M ;
Gerhard-Herman, M ;
Hollenberg, NK .
JOURNAL OF HYPERTENSION, 2003, 21 (12) :2281-2286