Transarterial chemoembolization with DC Bead LUMI™ radiopaque beads for primary liver cancer treatment: preliminary experience

被引：35

作者：

Aliberti, Camillo ^{[1
]}

Carandina, Riccardo ^{[1
]}

Sarti, Donatella ^{[2
]}

Pizzirani, Enrico ^{[1
]}

Ramondo, Gaetano ^{[1
]}

Cillo, Umberto ^{[3
]}

Guadagni, Stefano ^{[4
,5
]}

Fiorentini, Giammaria ^{[2
]}

机构：

[1] Inst Res & Treatment Canc IRCC, Oncol Inst Veneto, Oncol Radiodiagnost Dept, I-35128 Padua, Italy

[2] Azienda Osped Osped Riuniti Marche Nord, Oncoematol Dept, I-61122 Pesaro, Italy

[3] Univ Padua, Surg & Gastroenterol Sci Dept, I-35128 Padua, Italy

[4] Univ Aquila, Dept Appl Clin Sci & Biotechnol, I-7100 Laquila, AQ, Italy

[5] Alma Mater Europaea ECM, Slovenska Ulica 17, Maribor, Slovenia

来源：

FUTURE ONCOLOGY | 2017年 / 13卷 / 25期

关键词：

arterially directed embolic therapy; chemoembolization; DC Bead LUMI radiopaque beads; hepatocellular carcinoma; TACE; DRUG-ELUTING BEADS; SYSTEMIC THERAPY; EMBOLIZATION; STATISTICS; TRIAL; HCC;

D O I：

10.2217/fon-2017-0364

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aim: Primary objectives of the study were to assess the safety of transarterial chemoembolization (TACE) using DC Bead LUMI (TM) for the treatment of hepatocellular carcinoma and beads distribution after TACE. Patients/methods: This was a prospective observational cohort study. The study included 44 hepatocellular carcinoma patients who were treated with TACE using DC Bead LUMI. Beads distribution was monitored 1 h after TACE by CT scan. Results: TACE had no intraprocedural complications. Observed side effects were of mild intensity and included pain in 5 (11%), fever in 4 (9%) and vomiting in 2 (5%) patients. Most patients (89%) reported no adverse event. Non-target distribution was observed in only two cases (5%). Conclusion: DC Bead LUMI allowed assessing in real time their distribution. This could prevent non-target infusion and reduce toxicity.

引用

页码：2243 / 2252

页数：10

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