Imaging endogenous HClO in atherosclerosis using a novel fast-response fluorescence probe

被引:59
作者
Wang, Beibei [1 ,2 ]
Zhang, Feng [3 ]
Wang, Shukun [1 ]
Yang, Ruijin [1 ]
Chen, Chonghao [3 ]
Zhao, Wei [1 ,2 ]
机构
[1] Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China
[2] Jiangnan Univ, Jiangsu Key Lab Adv Food Mfg Equipment & Technol, Wuxi, Jiangsu, Peoples R China
[3] Jiangnan Univ, Affiliated Hosp, Wuxi Third Peoples Hosp, Wuxi 214122, Jiangsu, Peoples R China
关键词
HYPOCHLOROUS ACID DETECTION; SELECTIVE DETECTION; LIVE-CELL; MYELOPEROXIDASE; MITOCHONDRIA; EMISSION; HOCL; RED; CHEMODOSIMETER; OXIDATION;
D O I
10.1039/c9cc07256j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel pyrene-based naked-eye colorimetric and fluorescent turn-on probe (S-ClO) was developed. Besides, imaging in living RAW264.7 cells, an arterial vessel inflammation nude mouse model and human serum using S-ClO indicates that S-ClO could serve as a potential tool for early diagnosing and monitoring inflammatory diseases.
引用
收藏
页码:2598 / 2601
页数:4
相关论文
共 48 条
[1]   A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism [J].
Cheng, Tanyu ;
Zhao, Junwei ;
Wang, Ziyun ;
An, Juzeng ;
Xu, Yufang ;
Qian, Xuhong ;
Liu, Guohua .
DYES AND PIGMENTS, 2016, 126 :218-223
[2]   A "turn-on" fluorescent probe for hypochlorous acid: convenient synthesis, good sensing performance, and a new design strategy by the removal of C=N isomerization [J].
Cheng, Xiaohong ;
Jia, Huizhen ;
Long, Teng ;
Feng, Jun ;
Qin, Jingui ;
Li, Zhen .
CHEMICAL COMMUNICATIONS, 2011, 47 (43) :11978-11980
[3]   A dual analyte fluorescent chemosensor based on a furan-pyrene conjugate for Al3+ & HSO3- [J].
Don, Derin ;
Velmurugan, K. ;
Prabhu, J. ;
Bhuvanesh, N. ;
Thamilselvan, A. ;
Nandhakumar, R. .
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2017, 174 :62-69
[4]   A two-photon ratiometric fluorescent probe for the synergistic detection of the mitochondrial SO2/HClO crosstalk in cells and in vivo [J].
Dou, Kun ;
Chen, Guang ;
Yu, Fabiao ;
Sun, Zhiwei ;
Li, Guoliang ;
Zhao, Xianen ;
Chen, Lingxin ;
You, Jinmao .
JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (42) :8389-8398
[5]   MICROELECTRODE MEASUREMENT OF INTRACELLULAR PARAH OF MAMMALIAN HEART-CELLS [J].
ELLIS, D ;
THOMAS, RC .
NATURE, 1976, 262 (5565) :224-225
[6]   A fast-response, red emission aza-BODIPY-hydrazone-based chemodosimeter for selective detection of HClO [J].
Gao, Yuling ;
Pan, Yong ;
He, Yuanyuan ;
Chen, Haiyan ;
Nemykin, Victor N. .
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 269 :151-157
[7]   Measurement of intracellular (compartmental) pH by 31P NMR in Aspergillus niger [J].
Hesse, SJA ;
Ruijter, GJG ;
Dijkema, C ;
Visser, J .
JOURNAL OF BIOTECHNOLOGY, 2000, 77 (01) :5-15
[8]   Fluorescent liquid pyrene derivative-in-water microemulsions [J].
Hollamby, M. J. ;
Danks, A. E. ;
Schnepp, Z. ;
Rogers, S. E. ;
Hart, S. R. ;
Nakanishi, T. .
CHEMICAL COMMUNICATIONS, 2016, 52 (46) :7344-7347
[9]   Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging [J].
Hou, Ji-Ting ;
Wu, Ming-Yu ;
Li, Kun ;
Yang, Jin ;
Yu, Kang-Kang ;
Xie, Yang-Mel ;
Yu, Xiao-Qi .
CHEMICAL COMMUNICATIONS, 2014, 50 (63) :8640-8643
[10]   HKOCl-2 Series of Green BODIPY-Based Fluorescent Probes for Hypochlorous Acid Detection and Imaging in Live Cells [J].
Hu, Jun Jacob ;
Wong, Nai-Kei ;
Gu, Qiangshuai ;
Bai, Xiaoyu ;
Ye, Sen ;
Yang, Dan .
ORGANIC LETTERS, 2014, 16 (13) :3544-3547