Imaging endogenous HClO in atherosclerosis using a novel fast-response fluorescence probe

被引:58
作者
Wang, Beibei [1 ,2 ]
Zhang, Feng [3 ]
Wang, Shukun [1 ]
Yang, Ruijin [1 ]
Chen, Chonghao [3 ]
Zhao, Wei [1 ,2 ]
机构
[1] Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China
[2] Jiangnan Univ, Jiangsu Key Lab Adv Food Mfg Equipment & Technol, Wuxi, Jiangsu, Peoples R China
[3] Jiangnan Univ, Affiliated Hosp, Wuxi Third Peoples Hosp, Wuxi 214122, Jiangsu, Peoples R China
关键词
HYPOCHLOROUS ACID DETECTION; SELECTIVE DETECTION; LIVE-CELL; MYELOPEROXIDASE; MITOCHONDRIA; EMISSION; HOCL; RED; CHEMODOSIMETER; OXIDATION;
D O I
10.1039/c9cc07256j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel pyrene-based naked-eye colorimetric and fluorescent turn-on probe (S-ClO) was developed. Besides, imaging in living RAW264.7 cells, an arterial vessel inflammation nude mouse model and human serum using S-ClO indicates that S-ClO could serve as a potential tool for early diagnosing and monitoring inflammatory diseases.
引用
收藏
页码:2598 / 2601
页数:4
相关论文
共 48 条
  • [1] [Anonymous], ANGEW CHEM INT ED, DOI DOI 10.1002/ANGE.201500537
  • [2] A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism
    Cheng, Tanyu
    Zhao, Junwei
    Wang, Ziyun
    An, Juzeng
    Xu, Yufang
    Qian, Xuhong
    Liu, Guohua
    [J]. DYES AND PIGMENTS, 2016, 126 : 218 - 223
  • [3] A "turn-on" fluorescent probe for hypochlorous acid: convenient synthesis, good sensing performance, and a new design strategy by the removal of C=N isomerization
    Cheng, Xiaohong
    Jia, Huizhen
    Long, Teng
    Feng, Jun
    Qin, Jingui
    Li, Zhen
    [J]. CHEMICAL COMMUNICATIONS, 2011, 47 (43) : 11978 - 11980
  • [4] A dual analyte fluorescent chemosensor based on a furan-pyrene conjugate for Al3+ & HSO3-
    Don, Derin
    Velmurugan, K.
    Prabhu, J.
    Bhuvanesh, N.
    Thamilselvan, A.
    Nandhakumar, R.
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2017, 174 : 62 - 69
  • [5] A two-photon ratiometric fluorescent probe for the synergistic detection of the mitochondrial SO2/HClO crosstalk in cells and in vivo
    Dou, Kun
    Chen, Guang
    Yu, Fabiao
    Sun, Zhiwei
    Li, Guoliang
    Zhao, Xianen
    Chen, Lingxin
    You, Jinmao
    [J]. JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (42) : 8389 - 8398
  • [6] MICROELECTRODE MEASUREMENT OF INTRACELLULAR PARAH OF MAMMALIAN HEART-CELLS
    ELLIS, D
    THOMAS, RC
    [J]. NATURE, 1976, 262 (5565) : 224 - 225
  • [7] A fast-response, red emission aza-BODIPY-hydrazone-based chemodosimeter for selective detection of HClO
    Gao, Yuling
    Pan, Yong
    He, Yuanyuan
    Chen, Haiyan
    Nemykin, Victor N.
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2018, 269 : 151 - 157
  • [8] Measurement of intracellular (compartmental) pH by 31P NMR in Aspergillus niger
    Hesse, SJA
    Ruijter, GJG
    Dijkema, C
    Visser, J
    [J]. JOURNAL OF BIOTECHNOLOGY, 2000, 77 (01) : 5 - 15
  • [9] Fluorescent liquid pyrene derivative-in-water microemulsions
    Hollamby, M. J.
    Danks, A. E.
    Schnepp, Z.
    Rogers, S. E.
    Hart, S. R.
    Nakanishi, T.
    [J]. CHEMICAL COMMUNICATIONS, 2016, 52 (46) : 7344 - 7347
  • [10] Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging
    Hou, Ji-Ting
    Wu, Ming-Yu
    Li, Kun
    Yang, Jin
    Yu, Kang-Kang
    Xie, Yang-Mel
    Yu, Xiao-Qi
    [J]. CHEMICAL COMMUNICATIONS, 2014, 50 (63) : 8640 - 8643