Sex hormone testosterone affects language organization in the infant brain

被引：59

作者：

Friederici, Angela D. ^{[1
]}

Pannekamp, Ann ^{[1
]}

Partsch, Carl-Joachim ^{[2
]}

Ulmen, Ulrike ^{[3
]}

Oehler, Klaus ^{[4
]}

Schmutzler, Renate ^{[3
]}

Hesse, Volker ^{[3
,5
]}

机构：

[1] Max Planck Inst Human Cognit & Brain Sci, D-04103 Leipzig, Germany

[2] Stadt Kliniken Esslingen, Childrens Hosp, Esslingen, Germany

[3] Sana Klinikum Lichtenberg, Dept Pediat, Berlin, Germany

[4] Sana Klinikum Lichtenberg, Dept Lab Med, Berlin, Germany

[5] German Ctr Growth & Dev, Berlin, Germany

来源：

NEUROREPORT | 2008年 / 19卷 / 03期

关键词：

lateralization; phonological discrimination; testosterone;

D O I：

10.1097/WNR.0b013e3282f5105a

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Using a phonological discrimination paradigm, we show that the brain responses of 4-week-old infants systematically vary as a function of biological sex and testosterone level. Females who are generally low on testosterone demonstrated a clear phonological discrimination effect with a bilateral distribution. In male infants this effect systematically varied as a function of testosterone level. Males with high testosterone showed no discrimination effect, whereas males with low testosterone displayed a discrimination effect, which was clearly left-lateralized. The present data provide evidence for a strong influence of testosterone on language function and lateralization already present during the first weeks of life.

引用

页码：283 / 286

页数：4

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