Long noncoding RNA identification in lymphoma

被引:5
作者
Gu Siyu [1 ]
Zou Linqing [2 ]
Kong Linling [1 ]
Liu Hong [1 ]
Song Guoqi [1 ]
Cho, William C. [3 ]
机构
[1] Nantong Univ, Dept Med, Nantong 226001, Jiangsu, Peoples R China
[2] Nantong Univ, Dept Human Anat, Nantong 226001, Jiangsu, Peoples R China
[3] Queen Elizabeth Hosp, Dept Clin Oncol, Block R,30 Gascoigne Rd, Hong Kong, Hong Kong, Peoples R China
关键词
biomarkers; diagnosis; lncRNA; lymphoma; prognosis; therapeutic targets; B-CELL LYMPHOMA; HEALTH-ORGANIZATION CLASSIFICATION; POOR-PROGNOSIS; R-CHOP; LUNG-CANCER; HEPATOCELLULAR-CARCINOMA; MESSENGER-RNA; TUMOR-GROWTH; EXPRESSION; PREDICTS;
D O I
10.2217/fon-2017-0230
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
It has been found that long noncoding RNA (lncRNA) are abnormally expressed in lymphoma and play an important role in its pathogenesis. Through the detection and analysis of lncRNA, it was found that lncRNA could be used as an excellent biomarker for the diagnosis and prognosis of cancer. In lymphoma, abnormal lncRNA expression is associated with the patient's clinical characteristics, it can be used to determine the prognosis of the patient and serve as a therapeutic target in the disease.
引用
收藏
页码:2479 / 2487
页数:9
相关论文
共 74 条
[1]   Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project [J].
Birney, Ewan ;
Stamatoyannopoulos, John A. ;
Dutta, Anindya ;
Guigo, Roderic ;
Gingeras, Thomas R. ;
Margulies, Elliott H. ;
Weng, Zhiping ;
Snyder, Michael ;
Dermitzakis, Emmanouil T. ;
Stamatoyannopoulos, John A. ;
Thurman, Robert E. ;
Kuehn, Michael S. ;
Taylor, Christopher M. ;
Neph, Shane ;
Koch, Christoph M. ;
Asthana, Saurabh ;
Malhotra, Ankit ;
Adzhubei, Ivan ;
Greenbaum, Jason A. ;
Andrews, Robert M. ;
Flicek, Paul ;
Boyle, Patrick J. ;
Cao, Hua ;
Carter, Nigel P. ;
Clelland, Gayle K. ;
Davis, Sean ;
Day, Nathan ;
Dhami, Pawandeep ;
Dillon, Shane C. ;
Dorschner, Michael O. ;
Fiegler, Heike ;
Giresi, Paul G. ;
Goldy, Jeff ;
Hawrylycz, Michael ;
Haydock, Andrew ;
Humbert, Richard ;
James, Keith D. ;
Johnson, Brett E. ;
Johnson, Ericka M. ;
Frum, Tristan T. ;
Rosenzweig, Elizabeth R. ;
Karnani, Neerja ;
Lee, Kirsten ;
Lefebvre, Gregory C. ;
Navas, Patrick A. ;
Neri, Fidencio ;
Parker, Stephen C. J. ;
Sabo, Peter J. ;
Sandstrom, Richard ;
Shafer, Anthony .
NATURE, 2007, 447 (7146) :799-816
[2]   B cell receptor signaling in chronic lymphocytic leukemia [J].
Burger, Jan A. ;
Chiorazzi, Nicholas .
TRENDS IN IMMUNOLOGY, 2013, 34 (12) :592-601
[3]   The transcriptional landscape of the mammalian genome [J].
Carninci, P ;
Kasukawa, T ;
Katayama, S ;
Gough, J ;
Frith, MC ;
Maeda, N ;
Oyama, R ;
Ravasi, T ;
Lenhard, B ;
Wells, C ;
Kodzius, R ;
Shimokawa, K ;
Bajic, VB ;
Brenner, SE ;
Batalov, S ;
Forrest, ARR ;
Zavolan, M ;
Davis, MJ ;
Wilming, LG ;
Aidinis, V ;
Allen, JE ;
Ambesi-Impiombato, X ;
Apweiler, R ;
Aturaliya, RN ;
Bailey, TL ;
Bansal, M ;
Baxter, L ;
Beisel, KW ;
Bersano, T ;
Bono, H ;
Chalk, AM ;
Chiu, KP ;
Choudhary, V ;
Christoffels, A ;
Clutterbuck, DR ;
Crowe, ML ;
Dalla, E ;
Dalrymple, BP ;
de Bono, B ;
Della Gatta, G ;
di Bernardo, D ;
Down, T ;
Engstrom, P ;
Fagiolini, M ;
Faulkner, G ;
Fletcher, CF ;
Fukushima, T ;
Furuno, M ;
Futaki, S ;
Gariboldi, M .
SCIENCE, 2005, 309 (5740) :1559-1563
[4]   The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1 [J].
Chen, Jiahui ;
Liu, Lihui ;
Wei, Guifeng ;
Wu, Wei ;
Luo, Huaxia ;
Yuan, Jiao ;
Luo, Jianjun ;
Chen, Runsheng .
SCIENTIFIC REPORTS, 2016, 6
[5]   HUMAN C-MYC ONC GENE IS LOCATED ON THE REGION OF CHROMOSOME-8 THAT IS TRANSLOCATED IN BURKITT-LYMPHOMA CELLS [J].
DALLAFAVERA, R ;
BREGNI, M ;
ERIKSON, J ;
PATTERSON, D ;
GALLO, RC ;
CROCE, CM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (24) :7824-7827
[6]   The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression [J].
Derrien, Thomas ;
Johnson, Rory ;
Bussotti, Giovanni ;
Tanzer, Andrea ;
Djebali, Sarah ;
Tilgner, Hagen ;
Guernec, Gregory ;
Martin, David ;
Merkel, Angelika ;
Knowles, David G. ;
Lagarde, Julien ;
Veeravalli, Lavanya ;
Ruan, Xiaoan ;
Ruan, Yijun ;
Lassmann, Timo ;
Carninci, Piero ;
Brown, James B. ;
Lipovich, Leonard ;
Gonzalez, Jose M. ;
Thomas, Mark ;
Davis, Carrie A. ;
Shiekhattar, Ramin ;
Gingeras, Thomas R. ;
Hubbard, Tim J. ;
Notredame, Cedric ;
Harrow, Jennifer ;
Guigo, Roderic .
GENOME RESEARCH, 2012, 22 (09) :1775-1789
[7]   MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells [J].
Doose, Gero ;
Haake, Andrea ;
Bernhart, Stephan H. ;
Lopez, Cristina ;
Duggimpudi, Sujitha ;
Wojciech, Franziska ;
Bergmann, Anke K. ;
Borkhardt, Arndt ;
Burkhardt, Birgit ;
Claviez, Alexander ;
Dimitrova, Lora ;
Haas, Siegfried ;
Hoell, Jessica I. ;
Hummel, Michael ;
Karsch, Dennis ;
Klapper, Wolfram ;
Kleo, Karsten ;
Kretzmer, Helene ;
Kreuz, Markus ;
Kueppers, Ralf ;
Lawerenz, Chris ;
Lenze, Dido ;
Loeffler, Markus ;
Mantovani-Loeffler, Luisa ;
Moeller, Peter ;
Ott, German ;
Richter, Julia ;
Rohde, Marius ;
Rosenstiel, Philip ;
Rosenwald, Andreas ;
Schilhabel, Markus ;
Schneider, Markus ;
Scholz, Ingrid ;
Stilgenbauer, Stephan ;
Stunnenberg, Hendrik G. ;
Szczepanowski, Monika ;
Truemper, Lorenz ;
Weniger, Marc A. ;
Hoffmann, Steve ;
Siebert, Reiner ;
Iaccarino, Ingram .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (38) :E5261-E5270
[8]   The three-dimensional architecture of Hox cluster silencing [J].
Ferraiuolo, Maria A. ;
Rousseau, Mathieu ;
Miyamoto, Carol ;
Shenker, Solomon ;
Wang, Xue Qing David ;
Nadler, Michelle ;
Blanchette, Mathieu ;
Dostie, Josee .
NUCLEIC ACIDS RESEARCH, 2010, 38 (21) :7472-7484
[9]   Human Cancer Long Non-Coding RNA Transcriptomes [J].
Gibb, Ewan A. ;
Vucic, Emily A. ;
Enfield, Katey S. S. ;
Stewart, Greg L. ;
Lonergan, Kim M. ;
Kennett, Jennifer Y. ;
Becker-Santos, Daiana D. ;
MacAulay, Calum E. ;
Lam, Stephen ;
Brown, Carolyn J. ;
Lam, Wan L. .
PLOS ONE, 2011, 6 (10)
[10]   The functional role of long non-coding RNA in human carcinomas [J].
Gibb, Ewan A. ;
Brown, Carolyn J. ;
Lam, Wan L. .
MOLECULAR CANCER, 2011, 10