Prevention of deep-vein thrombosis and pulmonary embolism after spinal fracture with acute spinal cord injury.: Comparison of low-molecular-weight heparin and unfractionated heparin

被引：21

作者：

Lohmann, U ^{[1
]}

Gläser, E ^{[1
]}

Braun, BE ^{[1
]}

Bötel, U ^{[1
]}

机构：

[1] Univ Klin, BG Klin Bergmannsheil, Abt Neurotramatol & Ruckenmarkverletzte, D-44789 Bochum, Germany

来源：

ZENTRALBLATT FUR CHIRURGIE | 2001年 / 126卷 / 05期

关键词：

thromboembolism; high risk level; spinal cord injury; spinal fractures; low-molecular-weight heparin;

D O I：

10.1055/s-2001-14757

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In a prospective, randomized, open study, the therapeutic efficacy of a long-term prophylaxis with standard heparin (SH) was compared with that of low-molecular-weight heparin (LMWH) Dalteparin in 166 patients who had spinal fractures with spinal cord injury. 86 patients were treated with SH 2 x 7500 U s. c. and 80 patients were treated with LMWH 1 x 5000 anti-Xa U s. c. once daily. The screening was implemented by dayly bedside-examination. In case of clinical thromboembolism-symptoms patients had confirmatory venography or lung scans. In the SK-group 12 (14.0 %) patients had deep vein thrombosis and in the LMWH-group 6 (7.5 %). Pulmonary embolism was detected two times in the SH-group (2.33 %) acid only one time in the LMWH-group (1.25 %). A significant difference could not be shown, but is descriptive evident.

引用

页码：385 / 390

页数：6

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