Fluoroboric acid adsorbed on silica gel catalyzed synthesis of bisindolyl alkanes under mild and solvent-free conditions

被引：51

作者：

Bandgar, B. P. ^{[1
]}

Patil, Abasaheb. V. ^{[1
]}

Kamble, V. T. ^{[1
]}

机构：

[1] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Nanded 431606, Maharashtra, India

来源：

ARKIVOC | 2007年

关键词：

bisindolylmethanes; HBF4-SiO2; solvent-free reactions;

D O I：

10.3998/ark.5550190.0008.g25

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient electrophilic substitution of indoles with various carbonyl compounds and (1H- indol-3-yl)(alkyl) methanol were carried out smoothly using catalytic amount of HBF4-SiO2 under solvent free conditions to afford the symmetrical and unsymmetrical bis (indolyl) alkanes in good to excellent yields respectively. The method is simple, cost effective and gives good yields in short reaction times with recyclable catalyst.

引用

页码：252 / 259

页数：8

共 50 条

[1] Mannich-type reaction catalyzed by silica-supported fluoroboric acid under solvent-free conditions
Chen, WeiYi
Li, XinSheng
Lu, Jun
SYNTHETIC COMMUNICATIONS, 2008, 38 (04) : 546 - 552
[2] Catalytic activity of silica gel in the synthesis of sulfonamides under mild and solvent-free conditions
Jafarpour, Maasoumeh
Rezaeifard, Abdolreza
Aliabadi, Marzieh
APPLIED CATALYSIS A-GENERAL, 2009, 358 (01) : 49 - 53
[3] SILICA-GEL-CATALYZED EFFICIENT SYNTHESIS OF QUINOXALINE DERIVATIVES UNDER SOLVENT-FREE CONDITIONS
Nandi, Ganesh Chandra
Samai, Subhasis
Kumar, Ram
Singh, M. S.
SYNTHETIC COMMUNICATIONS, 2011, 41 (03) : 417 - 425
[4] Synthesis of chalcones catalyzed by aminopropylated silica sol-gel under solvent-free conditions
Romanelli, Gustavo
Pasquale, Gustavo
Sathicq, Angel
Thomas, Horacio
Autino, Juan
Vazquez, Patricia
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2011, 340 (1-2) : 24 - 32
[5] Silica gel catalyzed synthesis of quinophthalone pigments under solvent-free conditions using microwave irradiation
Loghmani-Khouzani, H
Sadeghi, MM
Safari, J
MOLECULES, 2002, 7 (02): : 135 - 139
[6] Selective oxidation of alcohols with potassium permanganate adsorbed on silica gel under solvent-free conditions
Lou, Ji-Dong
Pan, Li-Li
Li, Li
Li, Feng
Gao, Chun-Ling
SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2006, 36 (10) : 729 - 731
[7] An efficient synthesis of thiiranes from oxiranes using fluoroboric acid adsorbed on silica gel (HBF4-SiO2) as a catalyst under mild conditions in the absence of solvent
Bandgar, B. P.
Patil, Abasaheb V.
Kamble, V. T.
Totre, J. V.
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2007, 273 (1-2) : 114 - 117
[8] Silica supported fluoroboric acid as a novel, efficient and reusable catalyst for the synthesis of 1,5-benzodiazepines under solvent-free conditions
Bandgar, B. P.
Patil, Abasaheb V.
Chavan, O. S.
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 256 (1-2) : 99 - 105
[9] Lewis acid catalyzed synthesis of quinophthalone pigments under solvent-free conditions
Dehghan Khalili, Sh.
Banitabai Koupaie, S.H.
Safari, J.
Scientia Iranica, 2009, 16 (1 C) : 1 - 6
[10] TARTARIC ACID-CATALYZED SYNTHESIS OF α-AMINOPHOSPHONATES UNDER SOLVENT-FREE CONDITIONS
Gangwar, Nidhi
Kasana, Virendra Kumar
SYNTHETIC COMMUNICATIONS, 2011, 41 (18) : 2800 - 2804

← 1 2 3 4 5 →