Solubility of 6-aminopenicillanic acid in aqueous salt solutions from 273.15 K to 303.15 K

被引:18
作者
Su, Min [1 ]
Wang, Jingkang [1 ]
Hou, Yan [1 ]
机构
[1] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China
关键词
D O I
10.1021/je700284r
中图分类号
O414.1 [热力学];
学科分类号
摘要
The solubility of 6-aminopenicillanic acid in aqueous solutions of various concentrations of sodium sulfate and ammonium sulfate was determined from (274.15 to 303.15) K at atmospheric pressure using a synthetic method. Results showed that sodium sulfate has a salting-in effect on the solubility of 6-aminopenicillanic acid; ammonium sulfate has a salting-in effect if its concentration is below 0.5 M and a salting-out effect if its concentration is above 0.5 M. The solubility data were accurately correlated by a semiempirical equation.
引用
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页码:2266 / 2268
页数:3
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