Association between clinical parameters and the presence of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis in patients with progressive periodontal lesions

Background/Aim Periodontitis is a chronic inflammatory disease of periodontal tissues with consequential is bone loss as a result of host immunological reactions caused by periopathogens The aim of the study was to investigate if there is a correlation between clinical parameters and the presence of two most aggressive periopathogens (Aggregatibacter actinomycetemcomitans - Aa and Porphyromonas,gingivalis Pg) in patients with progressive periodontal lesions Methods A total of 34 systemic healthy people, 23 to 70 years old, were included in the study The patients were clinically and radiologically examined, and after that, the representative pocket with greatest pocket depth was chosen and the sample was collected from that place The measured clinic parameters were gingival index, index of gingival bleeding, pocket depth and plaque indices The multiplex Polymerase Chain Reaction (PCR) method was used for detection of periopathogens After obtaining results, appropriate statistical tests were used to correlate the clinical and microbiological results Results Aa and Pg were detected in the same percentage of samples Aa and Pg were detected in 35 29% samples alone, and in 29 41% both were detected The values of measured clinical parameters did not show a statistical significance between the groups in analysis of correlations among clinical parameters inside the groups, a statistical significance was found only between gingival and plaque index in the group with Aa Conclusion Clinical course of periodontitis in the developed stage does not differ m relation to the presence of different periopathogens as the major inductors of immunologically guided destructive processes