Oral metastatic hepatocellular carcinoma: A changing demographic in Europe and North America. Immunohistochemical advances in the microscopic diagnosis

被引：8

作者：

Daley, Thomas D. ^{[1
]}

Minett, Charles P. ^{[2
]}

Driman, David K. ^{[1
]}

Darling, Mark R. ^{[1
]}

机构：

[1] Univ Western Ontario, London Hlth Sci Ctr, Univ Hosp, Dept Pathol, London, ON N6A 5C1, Canada

[2] Univ Toronto, Div Oral & Maxillofacial Surg, Toronto, ON M5S 1A1, Canada

来源：

ORAL ONCOLOGY | 2011年 / 47卷 / 01期

关键词：

Neoplasm metastasis; Carcinoma; Hepatocellular; Jaw; Oral; Liver; CANCER STATISTICS; UNITED-STATES; TUMORS; GLYPICAN-3; SURVIVAL; TRENDS;

D O I：

10.1016/j.oraloncology.2010.07.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The incidence of hepatocellular carcinoma has shown an alarming increase in North America and Europe since 1980, as has the incidence of reported metastases to the oral region. Consequently, it is important that head and neck health care specialists be familiar with recent epidemiological trends and the histologic and recent immunohistochemical advances in the diagnosis of this deadly malignancy. Histologic features are reviewed, and recent advances in the immunohistochemical differential diagnosis are detailed and illustrated in two cases. A panel of immunohistochemical stains is recommended, some or all of which may be useful to differentiate poorly differentiated or pseudoglandular hepatocellular carcinoma from other metastatic adenocarcinomas to the oral and maxillofacial region. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：62 / 67

页数：6

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