A MYC Driven and Metabolite Executed Axis Controls the Subcellular Localization and Activity of TET DNA Hydroxylases and RNA Demethylases in B Cell Lymphomas

被引:0
|
作者
Qiu, Zhijun [1 ]
Lin, An-Ping [1 ]
Jiang, Shoulei [1 ]
Sasi, Binu [1 ]
Dahia, Patricia [1 ]
Zheng, Siyuan [2 ]
Aguiar, Ricardo [3 ]
机构
[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA
[2] Univ Texas Hlth Sci Ctr San Antonio, Dept Epidemiol & Biostat, San Antonio, TX 78229 USA
[3] South Texas Vet Hlth Care Syst, Audie Murphy VA Hosp, San Antonio, TX USA
关键词
D O I
10.1182/blood-2019-123101
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
114
引用
收藏
页数:3
相关论文
共 13 条
  • [1] MYC, mitochondrial metabolism and O-GlcNAcylation converge to modulate the activity and subcellular localization of DNA and RNA demethylases
    An-Ping Lin
    Zhijun Qiu
    Purushoth Ethiraj
    Binu Sasi
    Carine Jaafar
    Dinesh Rakheja
    Ricardo C. T. Aguiar
    Leukemia, 2022, 36 : 1150 - 1159
  • [2] MYC, mitochondrial metabolism and O-GlcNAcylation converge to modulate the activity and subcellular localization of DNA and RNA demethylases
    Lin, An-Ping
    Qiu, Zhijun
    Ethiraj, Purushoth
    Sasi, Binu
    Jaafar, Carine
    Rakheja, Dinesh
    Aguiar, Ricardo C. T.
    LEUKEMIA, 2022, 36 (04) : 1150 - 1159
  • [3] Altered Subcellular Localization of c-Myc Protein Identifies Aggressive B-cell Lymphomas Harboring a c-MYC Translocation
    Ruzinova, Marianna B.
    Caron, Tyler
    Rodig, Scott J.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2010, 34 (06) : 882 - 891
  • [4] Altered Subcellular Localization of the c-Myc Protein Distinguishes Burkitt Lymphoma from Aggressive B-Cell Lymphomas without a c-MYC Translocation
    Ruzinova, M. B.
    Caron, T.
    Rodig, S. J.
    MODERN PATHOLOGY, 2010, 23 : 319A - 320A
  • [5] Altered Subcellular Localization of the c-Myc Protein Distinguishes Burkitt Lymphoma from Aggressive B-Cell Lymphomas without a c-MYC Translocation
    Ruzinova, M. B.
    Caron, T.
    Rodig, S. J.
    LABORATORY INVESTIGATION, 2010, 90 : 319A - 320A
  • [6] Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas
    Shortt, Jake
    Martin, Benjamin P.
    Newbold, Andrea
    Hannan, Katherine M.
    Devlin, Jennifer R.
    Baker, Adele J.
    Ralli, Rachael
    Cullinane, Carleen
    Schmitt, Clemens A.
    Reimann, Maurice
    Hall, Michael N.
    Wall, Meaghan
    Hannan, Ross D.
    Pearson, Richard B.
    McArthur, Grant A.
    Johnstone, Ricky W.
    BLOOD, 2013, 121 (15) : 2964 - 2974
  • [7] Cell- and Virus-Mediated Regulation of the Barrier-to-Autointegration Factor's Phosphorylation State Controls Its DNA Binding, Dimerization, Subcellular Localization, and Antipoxviral Activity
    Jamin, Augusta
    Wicklund, April
    Wiebe, Matthew S.
    JOURNAL OF VIROLOGY, 2014, 88 (10) : 5342 - 5355
  • [8] Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas
    Benedetti, Rossella
    Arena, Andrea
    Romeo, Maria Anele
    Gilardini Montani, Maria Saveria
    Gonnella, Roberta
    Santarelli, Roberta
    Trivedi, Pankaj
    Cirone, Mara
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (16)
  • [9] Comparison Between Integrated Genomic DNA/RNA Profiling and Fluorescence In Situ Hybridization in the Detection of MYC, BCL-2, and BCL-6 Gene Rearrangements in Large B-Cell Lymphomas
    Cassidy, Daniel P.
    Chapman, Jennifer R.
    Lopez, Rafael
    White, Kyle
    Fan, Yao-Shan
    Casas, Carmen
    Severson, Eric A.
    Vega, Francisco
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2020, 153 (03) : 353 - 359
  • [10] Comparison Between Integrated Genomic DNA/RNA Profiling and Fluorescence In Situ Hybridization in the Detection of MYC, BCL-2, and BCL-6 Gene Rearrangements in Large B-Cell Lymphomas: An Update
    Guido, Luiz Paulo De Lima
    Chapman, Jennifer
    Cassidy, Daniel
    LABORATORY INVESTIGATION, 2022, 102 (SUPPL 1) : 937 - 938