Reirradiation of normal tissues: Preclinical radiobiological data

被引：6

作者：

Bourgier, C. ^{[1
]}

Vozenin, M. -C.

Deutsch, E.

机构：

[1] Inst Gustave Roussy, Dept Radiotherapie, F-94800 Villejuif, France

来源：

CANCER RADIOTHERAPIE | 2010年 / 14卷 / 6-7期

关键词：

Reirradiation; Normal tissues response; RADIATION-INDUCED FIBROSIS; INDUCED INTESTINAL INFLAMMATION; LONG-TERM RECOVERY; SPINAL-CORD; NECK-CANCER; TOLERANCE; DAMAGE; MOUSE; PENTOXIFYLLINE; RADIOTHERAPY;

D O I：

10.1016/j.canrad.2010.06.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Reirradiation represent an unfrequent particular clinical situation. The risk/benefit ratio assessment must be taken into account, considering both clinical and dosimetric aspects. There is a relatively limited amount of preclinical data available to date and clinicians should cautiously perform reirradiations in selected indications. This review summarizes the experimental data available on reirradiation of normal tissues, the consequences on early and late toxicities as well as the intrinsic limitations of these models. (C) 2010 Published by Elsevier Masson SAS on behalf of the Societe francaise de radiotherapie oncologique (SFRO).

引用

页码：412 / 415

页数：4

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