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Diperoxovanadate participates in peroxidation reactions of H2O2 in presence of abundant catalase
被引:15
作者:
Rao, AVS
[1
]
Ravishankar, HN
[1
]
Ramasarma, T
[1
]
机构:
[1] Indian Inst Sci, Dept Biochem, Bangalore 560012, Karnataka, India
来源:
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
|
1998年
/
1381卷
/
02期
关键词:
vanadate;
catalase;
H2O2;
diperoxovanadate;
D O I:
10.1016/S0304-4165(98)00038-5
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Vanadate forms a stable complex with H2O2 at pH 7.0 in competition with catalase and the product, diperoxovanadate, resists scavenger action of catalase. Diperoxovanadate can act as a substrate in a H2O2-user reaction, horseradish peroxidase and can take the place of H2O2 far more effectively in oxidatively inactivating glyceraldehyde-3-phosphate dehydrogenase. By forming peroxo-complexes vanadate can provide a way of preserving cellular H2O2 in presence of abundant catalase and make it available for its functions. (C) 1998 Elsevier Science B.V. All rights reserved.
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页码:249 / 255
页数:7
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