Positive ion electrospray ionization mass spectrometry of oligonucleotides

被引：47

作者：

SannesLowery, KA ^{[1
]}

Mack, DP ^{[1
]}

Hu, PF ^{[1
]}

Mei, HY ^{[1
]}

Loo, JA ^{[1
]}

机构：

[1] WARNER LAMBERT PARKE DAVIS,PARKE DAVIS PHARMACEUT RES,ANN ARBOR,MI 48105

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 1997年 / 8卷 / 01期

关键词：

D O I：

10.1016/S1044-0305(96)00202-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Positive ion electrospray ionization mass spectra have been obtained of deoxyribonucleic acids (DNA) and ribonucleic acids (RNA), including transfer RNAs (77-mer, similar to 25 kDa). For several different solution conditions, the charge state distributions of DNA and RNA molecules were determined. It is postulated that the production of the multiply charged positive ions results from gas phase dissociation of complexes between nitrogen-containing bases and oligonucleotides. (C) 1997 American Society for Mass Spectrometry

引用

页码：90 / 95

页数：6

共 32 条

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