Applications of Gold Nanoparticles in Non-Optical Biosensors

被引:92
作者
Jiang, Pengfei [1 ]
Wang, Yulin [1 ]
Zhao, Lan [1 ]
Ji, Chenyang [1 ]
Chen, Dongchu [2 ]
Nie, Libo [1 ]
机构
[1] Hunan Univ Technol, Hunan Key Lab Biomed Nanomat & Devices, Zhuzhou 412007, Peoples R China
[2] Foshan Univ, Sch Mat Sci & Energy Engn, Foshan 528000, Peoples R China
来源
NANOMATERIALS | 2018年 / 8卷 / 12期
关键词
gold nanoparticles; biosensor; piezoelectric; electrochemical; ICP-MS; QUARTZ-CRYSTAL MICROBALANCE; PLASMA-MASS SPECTROMETRY; SIGNAL AMPLIFICATION STRATEGY; ULTRASENSITIVE ELECTROCHEMICAL APTASENSOR; FUNCTIONALIZED AU NANOPARTICLES; ROLLING CIRCLE AMPLIFICATION; WALLED CARBON NANOTUBES; ICP-MS; COLLOIDAL GOLD; DNA HYBRIDIZATION;
D O I
10.3390/nano8120977
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Due to their unique properties, such as good biocompatibility, excellent conductivity, effective catalysis, high density, and high surface-to-volume ratio, gold nanoparticles (AuNPs) are widely used in the field of bioassay. Mainly, AuNPs used in optical biosensors have been described in some reviews. In this review, we highlight recent advances in AuNP-based non-optical bioassays, including piezoelectric biosensor, electrochemical biosensor, and inductively coupled plasma mass spectrometry (ICP-MS) bio-detection. Some representative examples are presented to illustrate the effect of AuNPs in non-optical bioassay and the mechanisms of AuNPs in improving detection performances are described. Finally, the review summarizes the future prospects of AuNPs in non-optical biosensors.
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页数:23
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