Unique Regulatory Mechanism for D-Galactose Utilization in Aspergillus nidulans

被引：37

作者：

Christensen, Ulla ^{[2
]}

Gruben, Birgit S. ^{[3
]}

Madrid, Susan ^{[2
,4
]}

Mulder, Harm ^{[2
,5
]}

Nikolaev, Igor ^{[2
,5
]}

de Vries, Ronald P. ^{[1
]}

机构：

[1] CBS KNAW Fungal Biodivers Ctr, NL-3584 CT Utrecht, Netherlands

[2] Danisco Innovat, DK-1001 Copenhagen, Denmark

[3] Univ Utrecht, Microbiol & Kluyver Ctr Genom Ind Fermentat, Utrecht, Netherlands

[4] Genencor Inc, Palo Alto, CA 94304 USA

[5] Genencor Inc, NL-2333 CN Leiden, Netherlands

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2011年 / 77卷 / 19期

关键词：

HYPOCREA-JECORINA; SACCHAROMYCES-CEREVISIAE; CELLULASE INDUCTION; LELOIR PATHWAY; GENE; METABOLISM; ENZYMES; YEAST; EXPRESSION; GROWTH;

D O I：

10.1128/AEM.05290-11

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

This study describes two novel regulators, GalX and GalR, that control D-galactose utilization in Aspergillus nidulans. This system is unique for A. nidulans since no GalR homologs were found in other ascomycetes. GalR shares significant sequence identity with the arabinanolytic and xylanolytic regulators AraR and XlnR, but GalX is more distantly related.

引用

页码：7084 / 7087

页数：4

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