An efficient iodine-DMSO catalyzed synthesis of quinoxaline derivatives

被引：37

作者：

Xie, Caixia ^{[1
]}

Zhang, Zeyuan ^{[1
]}

Yang, Bingchuan ^{[1
]}

Song, Gaolei ^{[1
]}

Gao, He ^{[1
]}

Wen, Leilin ^{[1
]}

Ma, Chen ^{[1
,2
,3
]}

机构：

[1] Shandong Univ, Sch Chem & Chem Engn, Key Lab Special Funct Aggregated Mat, Minist Educ, Jinan 250100, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China

[3] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

TETRAHEDRON | 2015年 / 71卷 / 12期

基金：

美国国家科学基金会;

关键词：

Quinoxaline; One-pot synthesis; Iodine/DMSO; Broad range of substrates; ONE-POT SYNTHESIS; OXIDATIVE SYSTEM; METHYL KETONES; TANDEM PROCESS; CONSTRUCTION; CYCLIZATION; STRATEGY; OXIDANT; DESIGN; ACID;

D O I：

10.1016/j.tet.2015.02.003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient iodine-DMSO catalyzed system for the synthesis of quinoxaline derivatives was developed. The construction of this quinoxaline system went through a one-pot oxidation/cyclization process. The reaction afforded a variety of products in good to excellent yields. This methodology has potential applications in the synthesis of biologically and medicinally relevant compounds. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：1831 / 1837

页数：7

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