Conformational analysis of enantiomers of chiral chloroalkanes

被引:0
|
作者
Gunasekaran, S [1 ]
Ponnambalam, U [1 ]
Sathyanarayanamoorthi, V [1 ]
机构
[1] Pachaiyappas Coll, Post Grad & Res Dept Phys, Madras 600030, Tamil Nadu, India
关键词
conformational analysis; enantiomers; 2-chloropentane; 2-chlorohexane; 2-chloroheptane;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The pairs of compounds that are nonsuperimposable mirror images called enantiomers. There are several classes of enantiomers that are being studied rather extensively because of their industrial and research importance. 2-Chloropentane, 2-chlorohexane and 2-chloroheptane are the most important chiral enantiomers. Conformational analysis is the study of the energies of different conformations. Many reactions depend on a molecule's ability to twist into a particular conformation. Conformational analysis can help to predict which conformations are favoured and which reactions are more likely to take place. Here we apply conformational analysis to these three enantiomers. From these we predict the most stable conformer. Besides that, the successful interpretations of these compounds using various parameters of the molecules have been provided.
引用
收藏
页码:239 / 244
页数:6
相关论文
共 50 条
  • [21] Adsorption of ibuprofen enantiomers on a chiral stationary phase with a grafted antibiotic eremomycin
    Reshetova, E. N.
    Asnin, L. D.
    RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A, 2015, 89 (02) : 275 - 281
  • [22] Separation of antofloxacin enantiomers by HPLC using chiral mobile phase additive
    Chen, Xi
    Yan, Leina
    Liu, Xuping
    Xiao, Qinqin
    Duan, Hexiang
    Zhang, Wenting
    Chen, Weikang
    Chinese Journal of Analysis Laboratory, 2021, 40 (08) : 918 - 921
  • [23] Separation of bifenthrin enantiomers by chiral HPLC and determination of their toxicity to aquatic organism
    Liu, TL
    Wang, YS
    Yen, JH
    JOURNAL OF FOOD AND DRUG ANALYSIS, 2005, 13 (04) : 357 - 360
  • [24] Adsorption of ibuprofen enantiomers on a chiral stationary phase with a grafted antibiotic eremomycin
    E. N. Reshetova
    L. D. Asnin
    Russian Journal of Physical Chemistry A, 2015, 89 : 275 - 281
  • [25] Separation of BINAPO enantiomers on brush-type chiral stationary phases
    Vinkovic, Vladimir
    Roje, Marin
    Kontrec, Darko
    Sunjic, Vitomir
    ARKIVOC, 2008, : 242 - 253
  • [26] CHIRAL LIQUID CHROMATOGRAPHIC METHOD DEVELOPMENT AND VALIDATION FOR SEPERATION OF PHENIRAMINE ENANTIOMERS
    Prava, Rajkumar
    Seru, Ganapathy
    Sama, Jayapal Reddy
    Sidhhanadham, Arun Satyadev
    INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 3 (12): : 1521 - 1533
  • [27] Analysis of carvedilol enantiomers in human plasma using chiral stationary phase column and liquid chromatography with tandem mass spectrometry
    Poggi, Josiane Cristofani
    Da Silva, Flavia Garcez
    Coelho, Eduardo Barbosa
    Marques, Maria Paula
    Bertucci, Carlo
    Lanchote, Vera Lucia
    CHIRALITY, 2012, 24 (03) : 209 - 214
  • [28] On the Study of Sorption in the Chiral Separation of the Enantiomers of Salbutamol and Salmeterol by Supercritical Fluid Chromatography
    Mikushina, Irina, V
    Bazarnova, Natalya G.
    Parenago, Olga O.
    Gensh, Konstantin, V
    Cheprasova, Marina Yu
    JOURNAL OF SIBERIAN FEDERAL UNIVERSITY-CHEMISTRY, 2019, 12 (03): : 310 - 318
  • [29] HPLC separation of 2-aryloxycarboxylic acid enantiomers on chiral stationary phases
    Tumashov, A. A.
    Vakarov, S. A.
    Sadretdinova, L. Sh
    Chulakov, E. N.
    Levit, G. L.
    Krasnov, V. P.
    Charushin, V. N.
    RUSSIAN CHEMICAL BULLETIN, 2021, 70 (05) : 900 - 907
  • [30] Separation of Enantiomers of Phenylalanine by HPLC Method With Different Types of Chiral Stationary Phases
    Lomenova, Anna
    Hrobonova, Katarina
    PROCEEDINGS OF THE 13TH INTERNATIONAL STUDENTS CONFERENCE MODERN ANALYTICAL CHEMISTRY, 2017, : 31 - 35