Genome-wide association studies for growth traits in broilers

被引：19
作者：
Dou, Dachang [1 ,2 ,3 ]
Shen, Linyong [1 ,2 ,3 ]
Zhou, Jiamei [1 ,2 ,3 ]
Cao, Zhiping [1 ,2 ,3 ]
Luan, Peng [1 ,2 ,3 ]
Li, Yumao [1 ,2 ,3 ]
Xiao, Fan [4 ]
Guo, Huaishun [4 ]
Li, Hui [1 ,2 ,3 ]
Zhang, Hui [1 ,2 ,3 ]
机构：
[1] Northeast Agr Univ, Key Lab Chicken Genet & Breeding, Minist Agr & Rural Affairs, Harbin 150030, Peoples R China
[2] Northeast Agr Univ, Key Lab Anim Genet Breeding & Reprod, Educ Dept Heilongjiang Prov, Harbin 150030, Peoples R China
[3] Northeast Agr Univ, Coll Anim Sci & Technol, Harbin 150030, Peoples R China
[4] Fujian Sunnzer Biotechnol Dev Co Ltd, Nanping 354100, Peoples R China
来源：
BMC GENOMIC DATA | 2022年 / 23卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Broiler; Growth trait; Body weight; GWAS; Heritability; GENETIC-PARAMETERS; LINES;
D O I：
10.1186/s12863-021-01017-7
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Background The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers. Results In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including ACTA1, IGF2BP1, TAPT1, LDB2, PRKCA, TGFBR2, GLI3, SLC16A7, INHBA, BAMBI, APCDD1, GPR39, and GATA4, were identified as important candidate genes for rapid growth in broilers. Conclusions The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers.
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页数：9
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