Fetal growth and the risk of childhood non-CNS solid tumours in Western Australia

被引:16
作者
Laurvick, C. L. [1 ]
Milne, E. [1 ]
Blair, E. [1 ]
de Klerk, N. [1 ]
Charles, A. K. [2 ,3 ,4 ,5 ]
Bower, C. [1 ]
机构
[1] Univ Western Australia, Telethon Inst Child Hlth Res, Ctr Child Hlth Res, Perth, WA 6872, Australia
[2] Univ Western Australia, Sch Paediat & Child Hlth, Subiaco, WA, Australia
[3] PMH Hosp, PathWest, Subiaco, WA, Australia
[4] KEMH Hosp, PathWest, Subiaco, WA, Australia
[5] Univ Western Australia, Sch Women & Infants Hlth, Subiaco, WA, Australia
基金
英国医学研究理事会;
关键词
childhood cancer; intra-uterine growth; risk factor; Cox regression;
D O I
10.1038/sj.bjc.6604424
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Using population-based linked health data, we investigated whether the risk of certain childhood non-CNS solid tumours (n = 186) was associated with intra-uterine growth. The risk of retinoblastoma and rhabdomyosarcoma, but not other tumour types, was positively associated with increased growth, suggesting a possible role of fetal growth factors. Larger studies are needed.
引用
收藏
页码:179 / 181
页数:3
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