DNA-free directed assembly in single-molecule cut-and-paste

被引：13

作者：

Erlich, Katherine R. ^{[1
,2
]}

Sedlak, Steffen M. ^{[1
,2
]}

Jobst, Markus A. ^{[1
,2
]}

Milles, Lukas F. ^{[1
,2
]}

Gaub, Hermann E. ^{[1
,2
]}

机构：

[1] Ludwig Maximilians Univ Munchen, Lehrstuhl Angew Phys, Amalienstr 54, D-80799 Munich, Germany

[2] Ludwig Maximilians Univ Munchen, Ctr NanoSci, Amalienstr 54, D-80799 Munich, Germany

来源：

NANOSCALE | 2019年 / 11卷 / 02期

关键词：

BINDING; ADHESION; STRENGTH; FORCE; TAG;

D O I：

10.1039/c8nr08636b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Single-molecule cut-and-paste facilitates bottom-up directed assembly of nanoscale biomolecular networks in defined geometries and enables analysis with spatio-temporal resolution. However, arrangement of diverse molecules of interest requires versatile handling systems. The novel DNA-free, genetically encodable scheme described here utilises an orthogonal handling strategy to promote arrangement of enzymes and enzyme networks.

引用

收藏

页码：407 / 411

页数：5

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