Fecal microbiota composition and frailty

被引：250
作者：
van Tongeren, SP
Slaets, JPJ
Harmsen, HJM
Welling, GW
机构：
[1] Univ Groningen, Ctr Med, Dept Med Microbiol, NL-9713 GZ Groningen, Netherlands
[2] Univ Groningen, Ctr Med, Dept Geriatr, NL-9713 GZ Groningen, Netherlands
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2005年 / 71卷 / 10期
关键词：
D O I：
10.1128/AEM.71.10.6438-6442.2005
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The relationship between fecal inicrobiota composition and frailty in the elderly was studied. Fecal samples from volunteers with high frailty scores showed a significant reduction in the number of lactobacilli (26-fold). At much higher population levels, both the Bacteroides/Prevotella (threefold) and the Faecalibacterium prausnitzii (fourfold) groups showed a significant reduction in percentage of total number of hybridizable bacteria in the elderly with high frailty scores. In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers.
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页码：6438 / 6442
页数：5
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