Effects of S-adenosyl methionine, ethanolamine, and their combination on lipid composition of rat brain in chronic alcohol intoxication

被引:0
作者
Selevich, MI [1 ]
机构
[1] Godno State Med Inst, Dept Biomed Problems Narcol, Grodno, BELARUS
关键词
brain; alcohol; phospholipids; glycolipids;
D O I
10.1007/BF02499154
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Brain lipids are studied in rats with chronic alcohol intoxication after injection of S-adenosyl methionine, ethanolamine, and their combination. The levels of total lipids, phospholipids, and cardiolipin are increased and those of sphyngomyelin and cerebrosides-III decreased after a 14-day inhalation of ethanol. Combined administration of S-adenosyl methionine and ethanolamine in chronic alcoholization eliminated ethanol-induced shifts in concentrations of phospho- and glycolipid fractions in rat brain.
引用
收藏
页码:351 / 352
页数:2
相关论文
共 13 条
  • [1] AVAGIMYAN E A, 1987, Biologicheskii Zhurnal Armenii, V40, P815
  • [2] FOLCH J, 1957, J BIOL CHEM, V226, P497
  • [3] HARPER C, 1994, ALCOHOL CLIN EXP RES, V18, pH6
  • [4] KARAGEZYAN KG, 1976, VOP MED KHIM, V22, P30
  • [5] KRSIAK M, 1971, ACTIV NERV SUPER, V13, P198
  • [6] LESCH P, 1972, Z KLIN CHEM KLIN BIO, V10, P410
  • [7] PROKHOROVA MI, 1982, METHODS BIOCH INVEST
  • [8] PROKHOROVA MI, 1965, ALABORATORY COURSE C
  • [9] INHIBITION OF PLASMA-MEMBRANE AND MITOCHONDRIAL TRANSMEMBRANE POTENTIALS BY ETHANOL
    SAMYNATHAN, YM
    BONDY, SC
    [J]. NEUROCHEMICAL RESEARCH, 1995, 20 (02) : 171 - 176
  • [10] EFFECT OF METHIONINE AND METHIONINE SULFOXIMINE ON RAT-BRAIN S-ADENOSYL METHIONINE LEVELS
    SCHATZ, RA
    SELLINGER, OZ
    [J]. JOURNAL OF NEUROCHEMISTRY, 1975, 24 (01) : 63 - 66