Therapeutic success of sodium thiosulfate in treating cutaneous calciphylaxis in a patient with hyperphosphataemic familial tumoral calcinosis

被引：2
|
作者：
Requena, Sheila [1 ]
Santos-Juanes, Jorge [1 ]
Morales, Patricia [2 ]
Gomez, Carlos [3 ]
机构：
[1] Hosp Univ Cent Asturias, Dept Dermatol, C Avenida Roma S-N, Oviedo 33011, Spain
[2] Hosp Univ Cent Asturias, Dept Pathol Anat, Oviedo, Spain
[3] Hosp Univ Cent Asturias, Dept Metab, Oviedo, Spain
来源：
AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2022年 / 63卷 / 01期
关键词：
calciphylaxis; hyperphosphatemic familial tumoral calcinosis; topical sodium thiosulfate;
D O I：
10.1111/ajd.13750
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Calciphylaxis is a potencially disorder in patients with hyperphosphatemic familial tumoral calcinosis (HFTC). Patients commonly present livedo racemosa and retiform purpura, which may progress to necrosis and very painful ulcers. Treatment with sodium thiosulfate provides good results; however, intralesional and intravenous treatment can be limited by its adverse effects. Topical sodium thiosulfate has been successfully reported for cutaneous calcification associated with connective tissue diseases and calciphylaxis in patients with chronic kidney disease. We provide a case report of a patient with HFTC and calciphylaxis who was treated with topical sodium thiosulfate with a rapid and complete response with no side effects.
引用
收藏
页码：E75 / E77
页数：3
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