A glycerol α-d-glucuronide and a megastigmane glycoside from the leaves of Guettarda speciosa L.

被引：30

作者：

Cai, Wen-Hu ^{[1
]}

Matsunami, Katsuyoshi ^{[1
]}

Otsuka, Hideaki ^{[1
]}

Shinzato, Takakazu ^{[2
]}

Takeda, Yoshio ^{[3
]}

机构：

[1] Hiroshima Univ, Grad Sch Biomed Sci, Minami Ku, Hiroshima 7348553, Japan

[2] Univ Ryukyus, Subtrop Field Sci Ctr, Fac Agr, Nishihara, Okinawa 9030213, Japan

[3] Yasuda Womens Univ, Fac Pharm, Asaminami Ku, Hiroshima 7310153, Japan

来源：

JOURNAL OF NATURAL MEDICINES | 2011年 / 65卷 / 02期

基金：

日本学术振兴会;

关键词：

Guettarda speciosa; Rubiaceae; Glycerol alpha-glucuronide; Megastigmane glycoside; QUINOVIC ACID GLYCOSIDES; GLUCOSIDE;

D O I：

10.1007/s11418-010-0484-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

From the 1-BuOH-soluble fraction of a MeOH extract of the leaves of Guettarda speciosa L., two new compounds (1, 2) were isolated together with six known compounds. Spectroscopic analysis of 1 and 2 established their structures to be derivatives of a glycerol alpha-glucuronide and a megastigmane glycoside, respectively. HPLC analysis of the hydrolyzate of 1 confirmed the presence of d-glucuronic acid in the structure, and the modified Mosher's method established the absolute structure of 2.

引用

页码：364 / 369

页数：6

共 19 条

[1] FURTHER QUINOVIC ACID GLYCOSIDES FROM GUETTARDA-PLATYPODA [J].

AQUINO, R ;

DESIMONE, F ;

PIZZA, C ;

DEMELLO, JF .

PHYTOCHEMISTRY, 1989, 28 (01) :199-201

[2] QUINOVIC ACID GLYCOSIDES FROM GUETTARDA-PLATYPODA [J].

AQUINO, R ;

DESIMONE, F ;

PIZZA, C ;

CERRI, R ;

DEMELLO, JF .

PHYTOCHEMISTRY, 1988, 27 (09) :2927-2930

[3] IRIDOIDS - AN UPDATED REVIEW .2. [J].

BOROS, CA ;

STERMITZ, FR .

JOURNAL OF NATURAL PRODUCTS, 1991, 54 (05) :1173-1246

[4] Constituents of Cydonia vulgaris: Isolation and structure elucidation of four new flavonol glycosides and nine new alpha-ionol-derived glycosides [J].

DeTommasi, N ;

Piacente, S ;

DeSimone, F ;

Pizza, C .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1996, 44 (07) :1676-1681

[5] STRUCTURES OF NATURAL-PRODUCTS BLUMENOLS A, B, AND C [J].

GALBRAITH, MN ;

HORN, DHS .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1972, (03) :113-+

[6] NMR SPECTRAL-ANALYSIS OF CADAMBINE FROM ANTHOCEPHALUS-CHINENSIS [J].

HANDA, SS ;

BORRIS, RP ;

CORDELL, GA ;

PHILLIPSON, JD .

JOURNAL OF NATURAL PRODUCTS, 1983, 46 (03) :325-330

[7]

HATUSIMA S, 1975, FLORA RYUKYUS ADDED, P569

[8] EPI-3 ANTIRHINE, A NEW EXTRACT OF GUETTARDA-HETEROSEPALA [J].

KANFAN, C ;

BRILLANCEAU, MH ;

HUSSON, HP .

JOURNAL OF NATURAL PRODUCTS, 1986, 49 (06) :1130-1132

[9] Chemical markers in Veronica sect. Hebe. III [J].

Maggi, Agnese ;

Taskova, Rilka ;

Gotfredsen, Charlotte Held ;

Bianco, Armandodoriani ;

Jensen, Soren Rosendal .

BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2009, 37 (06) :731-736

[10] QUINOVIC ACID GLYCOSIDES FROM GUETTARDA-ANGELICA [J].

MATOS, MEO ;

SOUSA, MP ;

MACHADO, MIL ;

BRAZ FILHO, R .

PHYTOCHEMISTRY, 1986, 25 (06) :1419-1422

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